Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.61 |
| ▸ | ADORA1 | P30542 | 14/20 | 0.56 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.56 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.55 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7064488 | 0.91 | ADORA3 (0.65) | ADORA3ADORA1TAS1R3TAS1R1ADORA2A | |
| SCHEMBL6663637 | 0.91 | ADORA3 (0.72) | ADORA3ADORA1TAS1R3TAS1R1ADORA2A | |
| SCHEMBL7121616 | 0.91 | ADORA3 (0.52) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL7067588 | 0.83 | ADORA1 (0.77) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL7067593 | 0.83 | ADORA1 (0.77) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL7068557 | 0.82 | ADORA3 (0.54) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL7064261 | 0.82 | ADORA2A (0.68) | ADORA3ADORA1TAS1R3TAS1R1ADORA2A | |
| SCHEMBL6658486 | 0.81 | ADORA3 (0.76) | ADORA3ADORA1TAS1R3TAS1R1ADORA2A | |
| SCHEMBL6253676 | 0.81 | ADORA1 (0.70) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL6574568 | 0.80 | ADORA3 (0.51) | ADORA3ADORA1ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027363-B1 | ADENOSINE A1-RECEPTOR AGONISTS | GLAXO GROUP LTD (GB) | 2003-06-04 | — | — | EP | claimed |