Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | PI4KA | P42356 | 1/20 | 0.47 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.47 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.47 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.46 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.44 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | AMD1 | P17707 | 2/20 | 0.40 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7533606 | 0.88 | RXFP1 (0.47) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL9620376 | 0.88 | PI4KA (0.61) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL260626 | 0.88 | PI4KA (0.61) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL14174700 | 0.88 | RXFP1 (0.45) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL6659329 | 0.85 | RXFP1 (0.59) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL6659324 | 0.85 | RXFP1 (0.59) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL6663776 | 0.81 | ADORA3 (0.69) | ADORA3LMNATP53NT5E | |
| SCHEMBL7528154 | 0.79 | PI4KA (0.48) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL23914964 | 0.78 | LMNA (0.65) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL18493278 | 0.78 | LMNA (0.65) | RXFP1PI4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1030856-B1 | ADENOSINE A1 RECEPTOR AGONISTS | GLAXO GROUP LTD (GB) | 2004-08-18 | — | — | EP | disclosed |
| US-6740644-B2 | ADENOSINE DERIVATIVES, AGONISTS AT THE ADENOSINE A1 RECEPTOR | SMITHKLINE BEECHAM CORPORATION | 2004-05-25 | — | — | US | disclosed |
| US-20030158146-A1 | Chemical compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2003-08-21 | — | — | US | disclosed |
| US-6544960-B1 | Chemical compounds | SMITHKLINE BEECHAM CORPORATION | 2003-04-08 | — | — | US | disclosed |
| EP-0901499-B1 | ADENOSINE DERIVATIVES | GLAXO GROUP LTD (GB) | 2002-04-10 | — | — | EP | disclosed |
| US-5998388-A | N6-PHENYL-SUBSTITUTED | GLAXO WELLCOME INC. (US) | 1999-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030158146-A1 | Chemical compounds | CNR1, ADORA3, ADORA1 | RXFP1 197/4885PI4KA 4479/4885PI4K2B 4606/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.