Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.48 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.48 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.48 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.45 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.45 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | AMD1 | P17707 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7533606 | 0.89 | RXFP1 (0.47) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL307825 | 0.79 | PI4KA (0.65) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL6663698 | 0.79 | RXFP1 (0.48) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL24981785 | 0.77 | RXFP1 (0.50) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL6659329 | 0.76 | RXFP1 (0.59) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL6659324 | 0.76 | RXFP1 (0.59) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL9620170 | 0.76 | PI4KA (0.77) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL260752 | 0.75 | PI4KA (0.69) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL260760 | 0.75 | PI4KA (0.59) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL18512558 | 0.74 | PI4KA (0.58) | PI4KAPI4K2BPI4K2API4KBRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901499-B1 | ADENOSINE DERIVATIVES | GLAXO GROUP LTD (GB) | 2002-04-10 | — | — | EP | disclosed |
| US-5998388-A | N6-PHENYL-SUBSTITUTED | GLAXO WELLCOME INC. (US) | 1999-12-07 | — | — | US | disclosed |