SCHEMBL8729170

SCHEMBL8729170

NC(c1ccccc1)C(C(c1ccccc1)c1ccccc1)P(=O)(O)O

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.50
DPP4 P27487 2/20 0.48
ACP3 P15309 6/20 0.43
ANPEP P15144 4/20 0.43
LAP3 P28838 3/20 0.43
ERAP1 Q9NZ08 2/20 0.41
ERAP2 Q6P179 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8729175 1.00 SRC (0.50) SRCDPP4ACP3ANPEPLAP3
SCHEMBL6663785 0.77 DPP4 (0.43) DPP4ACP3ANPEPLAP3
SCHEMBL6663146 0.75 ANPEP (0.45) SRCACP3ANPEPLAP3
SCHEMBL14831728 0.74 SRC (0.52) SRCDPP4ACP3ANPEPLAP3
SCHEMBL14818488 0.73 SRC (0.50) SRCDPP4ACP3ANPEPLAP3
Amino(Phenyl)Methylphosphonic Acid SCHEMBL5223252 0.73 SRC (0.60) SRCDPP4ACP3ANPEPLAP3
Amino(Phenyl)Methylphosphonic Acid SCHEMBL7647462 0.73 SRC (0.60) SRCDPP4ACP3ANPEPLAP3
Amino(Phenyl)Methylphosphonic Acid SCHEMBL233491 0.73 SRC (0.60) SRCDPP4ACP3ANPEPLAP3
SCHEMBL14818493 0.72 SRC (0.48) SRCDPP4ACP3ANPEPLAP3
SCHEMBL1143444 0.71 DPP4 (0.72) DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0877028-A1 PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE 1-AMINOPHOSPHONIC ACID DERIVATIVES AND NOVEL PHOSPHONATE COMPOUNDS HOKKO CHEMICAL INDUSTRY CO. LTD. (JP) 1998-11-11 EP disclosed