SCHEMBL6663864

SCHEMBL6663864

C=CCCC1CCC(c2ccc(C(F)(F)OC(C)c3ccc(OC(F)(F)F)cc3)cc2)CC1

nearest known ligand 0.33

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ACACB O00763 4/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
GPR139 Q6DWJ6 1/20 0.32
PDE2A O00408 4/20 0.31
KDM1A O60341 1/20 0.31
RCOR1 Q9UKL0 1/20 0.31
EPHX2 P34913 1/20 0.30
HRH3 Q9Y5N1 1/20 0.30
PTGS2 P35354 1/20 0.30
PSEN1 P49768 1/20 0.30
PSEN2 P49810 1/20 0.30
SPPL2B Q8TCT7 1/20 0.30
SPPL2A Q8TCT8 1/20 0.30
APH1B Q8WW43 1/20 0.30
NCSTN Q92542 1/20 0.30
APH1A Q96BI3 1/20 0.30
PSENEN Q9NZ42 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6665868 0.93 ACACB (0.33) ACACB
SCHEMBL6667704 0.90 HTR2C (0.36) ACACBPSEN1PSEN2APH1BNCSTN
SCHEMBL6661265 0.89 GPR139 (0.32) ACACBL3MBTL1GPR139PDE2AKDM1A
SCHEMBL6665432 0.89 ALDH1A1 (0.33) ACACB
SCHEMBL6665640 0.89 ESR2 (0.33) ACACB
SCHEMBL6665115 0.89 ALDH1A1 (0.40) ACACB
SCHEMBL6662956 0.89 ACACB (0.31) ACACB
SCHEMBL6664066 0.89 ACACB (0.31) ACACB
SCHEMBL6664874 0.88 L3MBTL1 (0.34) L3MBTL1GPR139PDE2AKDM1ARCOR1
SCHEMBL6662713 0.88 ALDH1A1 (0.40) ACACBL3MBTL1GPR139PDE2AKDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0893423-B1 LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED LINKAGES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES CHISSO CORP (JP) 2004-09-01 EP disclosed