Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | GAA | P10253 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13149786 | 0.81 | ALDH1A1 (1.00) | ALDH1A1GAALMNAMAPTALOX12 | |
| SCHEMBL11293119 | 0.80 | GAA (0.85) | ALDH1A1GAALMNAMAPTALOX12 | |
| SCHEMBL6664861 | 0.78 | ALDH1A1 (0.56) | ALDH1A1GAALMNAMAPTALOX12 | |
| SCHEMBL11739483 | 0.77 | ADRA1A (0.67) | ALDH1A1GAALMNAMAPTNPC1 | |
| SCHEMBL6712582 | 0.77 | MAPT (1.00) | ALDH1A1GAALMNAMAPTALOX12 | |
| SCHEMBL10979081 | 0.75 | GAA (0.72) | ALDH1A1GAALMNAMAPTALOX12 | |
| SCHEMBL9187774 | 0.75 | GAA (0.72) | ALDH1A1GAALMNAMAPTALOX12 | |
| SCHEMBL10280045 | 0.74 | GAA (0.74) | ALDH1A1GAALMNAMAPTALOX12 | |
| SCHEMBL6651783 | 0.73 | ALDH1A1 (0.70) | ALDH1A1GAALMNAMAPTALOX12 | |
| SCHEMBL6650909 | 0.73 | ALDH1A1 (0.70) | ALDH1A1GAALMNAMAPTALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014376-A1 | GAL3 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF AFFECTIVE DISORDERS | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 2004-02-19 | — | — | WO | disclosed |