SCHEMBL6663974

SCHEMBL6663974

CC(C)c1c(N)ccc(O)c1C(C)C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.48
GAA P10253 4/20 0.48
ALOX12 P18054 2/20 0.48
HTT P42858 1/20 0.48
HIF1A Q16665 1/20 0.48
ALOX15 P16050 5/20 0.38
HSD17B10 Q99714 4/20 0.38
HPGD P15428 3/20 0.38
PKM P14618 2/20 0.38
USP2 O75604 1/20 0.38
IDO1 P14902 2/20 0.38
HDAC3 O15379 1/20 0.38
EP300 Q09472 1/20 0.38
KAT2B Q92831 1/20 0.38
KAT8 Q9H7Z6 1/20 0.38
NCOR2 Q9Y618 1/20 0.38
CSNK2A2 P19784 1/20 0.37
CSNK2B P67870 1/20 0.37
CSNK2A1 P68400 1/20 0.37
CSNK2A3 Q8NEV1 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL924270 0.84 ALDH1A1 (0.37) ALDH1A1GAAALOX12HTTHIF1A
SCHEMBL1760433 0.84 TYR (0.44) ALDH1A1GAAALOX12HTTHIF1A
SCHEMBL30360391 0.84 TYR (0.44) ALDH1A1GAAALOX12HTTHIF1A
SCHEMBL15934285 0.79 TSHR (0.48) ALDH1A1GAAALOX12HTTHIF1A
SCHEMBL28423389 0.78 ALDH1A1 (0.40) ALDH1A1GAAALOX12HTTHIF1A
SCHEMBL25229039 0.73 TRPA1 (0.46) ALDH1A1GAAALOX12HTTHIF1A
SCHEMBL1532606 0.73 CYP3A4 (0.37) ALDH1A1GAAALOX12HTTHIF1A
SCHEMBL478565 0.73 LMNA (0.46) ALDH1A1GAAALOX12HTTHIF1A
SCHEMBL1228797 0.73 LMNA (0.32) ALDH1A1GAAALOX12HTTHIF1A
SCHEMBL27719080 0.73 GAA (0.47) ALDH1A1GAAALOX12HTTHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100366233-C Hair conditioning compositions and application in hair dye composition thereof PROCTER & GAMBLE (US) 2008-02-06 CN disclosed
CN-1239642-C Anthraquinone compound and aqueous ink for inkjet recording using the same MITSUI CHEMICALS INC (JP) 2006-02-01 CN disclosed
CN-1209094-C Hair coloring compositions and methods PROCTER & GAMBLE (US) 2005-07-06 CN disclosed
CN-1153562-C Hair coloring compositions ���޿��غ͸ʱ�����˾ 2004-06-16 CN disclosed
CN-1479606-A Hair conditioning composition and use thereof in hair dyeing compositions 宝洁公司 2004-03-03 CN disclosed
WO-2004014328-A1 ONE STEP HAIR COLORING COMPOSITIONS COMPRISING WATER SOLUBLE CARBONATE RELEASING SALTS UNILEVER PLC (GB) 2004-02-19 WO disclosed
CN-1427711-A Hair colouring and conditioning composition PROCTER & GAMBLE (US) 2003-07-02 CN disclosed
CN-1427710-A Composition for colouring and conditioning hair PROCTER & GAMBLE (US) 2003-07-02 CN disclosed
WO-2003047542-A1 HAIR BLEACHING AND COLOURING COMPOSITION WHICH COMPRISE TRASITION METAL CATALYSTS UNILEVER PLC (GB) 2003-06-12 WO disclosed
CN-1411361-A Hair coloring compositions and methods PROCTER & GAMBLE (US) 2003-04-16 CN disclosed
EP-0876134-A1 HAIR COLORING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1998-11-11 EP disclosed
EP-0869769-A1 HAIR BLEACHING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1998-10-14 EP disclosed
WO-1998027943-A1 HAIR COLORING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1998-07-02 WO disclosed
WO-1998027941-A1 HAIR COLORING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1998-07-02 WO disclosed
WO-1998027942-A1 HAIR COLORING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1998-07-02 WO disclosed
WO-1998027944-A1 HAIR COLORING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1998-07-02 WO disclosed
WO-1998027945-A1 HAIR COLORING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1998-07-02 WO disclosed
WO-1997024105-A1 HAIR COLORING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1997-07-10 WO disclosed
WO-1997024108-A1 HAIR BLEACHING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1997-07-10 WO disclosed
WO-1997024107-A1 HAIR COLORING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1997-07-10 WO disclosed