Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | NCF1 | P14598 | 2/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3267344 | 0.78 | NCF1 (0.43) | ALDH1A1HSD17B10KDM4EGAACYP1A2 | |
| SCHEMBL26512422 | 0.77 | NCF1 (0.42) | ALDH1A1HSD17B10KDM4EGAACYP1A2 | |
| SCHEMBL31376529 | 0.75 | ALDH1A1 (0.59) | ALDH1A1HSD17B10KDM4EGAACYP1A2 | |
| SCHEMBL1848409 | 0.75 | ALDH1A1 (0.59) | ALDH1A1HSD17B10KDM4EGAACYP1A2 | |
| SCHEMBL28320052 | 0.74 | ALDH1A1 (0.46) | ALDH1A1HSD17B10KDM4EGAACYP1A2 | |
| SCHEMBL11251120 | 0.74 | NCF1 (0.40) | ALDH1A1HSD17B10KDM4EGAACYP1A2 | |
| SCHEMBL18704072 | 0.73 | ALDH1A1 (0.54) | ALDH1A1HSD17B10KDM4EGAACYP1A2 | |
| SCHEMBL7995244 | 0.72 | ALDH1A1 (0.51) | ALDH1A1HSD17B10KDM4EGAACYP1A2 | |
| SCHEMBL29157816 | 0.71 | CYP1A2 (0.41) | ALDH1A1HSD17B10KDM4EGAACYP1A2 | |
| SCHEMBL10020390 | 0.70 | ALDH1A1 (0.53) | ALDH1A1HSD17B10KDM4EGAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1251123-B1 | PROCESS FOR PREPARING QUINOLYLACRYLONITRILE AND INTERMEDIATES THEREFOR | NISSAN CHEMICAL IND LTD (JP) | 2004-07-21 | — | — | EP | disclosed |
| US-6541636-B2 | Such as 3-(2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolyl) prop-2-enenitrile by reacting 2-cyclopropyl-4-(4-fluorophenyl) quinoline-3-carbaldehyde with acetonitrile in the presence of base, then dehydrating; enzyme inhibitors | UBE INDUSTRIES, LTD. (JP) | 2003-04-01 | — | — | US | disclosed |
| US-20030013885-A1 | PROCESS FOR PREPARING QUINOLYLACRYLONITRILE AND INTERMEDIATES THEREFOR | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2003-01-16 | — | — | US | disclosed |
| EP-1251123-A1 | PROCESS FOR PREPARING QUINOLYLACRYLONITRILE AND INTERMEDIATES THEREFOR | Ube Industries, Ltd. (JP) | 2002-10-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030013885-A1 | PROCESS FOR PREPARING QUINOLYLACRYLONITRILE AND INTERMEDIATES THEREFOR | WEE2, WEE1, CYP4F11 | ALDH1A1 643/4885HSD17B10 1271/4885KDM4E 3444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.