Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3267344 | 0.86 | NCF1 (0.43) | NCF1CYP1A2NOS2BACE1CA12 | |
| SCHEMBL11251120 | 0.81 | NCF1 (0.40) | NCF1CYP1A2NOS2BACE1CA12 | |
| SCHEMBL404595 | 0.80 | NCF1 (0.42) | NCF1CYP1A2NOS2BACE1CA12 | |
| SCHEMBL7995244 | 0.79 | ALDH1A1 (0.51) | NCF1CYP1A2NOS2BACE1CA12 | |
| SCHEMBL6663983 | 0.77 | ALDH1A1 (0.43) | NCF1CYP1A2NOS2BACE1CA12 | |
| SCHEMBL11813236 | 0.77 | NCF1 (0.44) | NCF1CYP1A2NOS2BACE1CA12 | |
| SCHEMBL9009627 | 0.76 | NCF1 (0.50) | NCF1CYP1A2NOS2BACE1CA12 | |
| SCHEMBL8035416 | 0.75 | L3MBTL1 (0.45) | CYP1A2ALDH1A1HSD17B10NPC1RAB9A | |
| SCHEMBL28580719 | 0.74 | MAPT (0.49) | ALDH1A1HSD17B10KDM4ENPC1RAB9A | |
| SCHEMBL10578784 | 0.74 | L3MBTL1 (0.44) | CYP1A2ALDH1A1HSD17B10KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118059257-A | Preparation method of cathepsin E response preparation and pancreatic cancer specific photodiagnosis and treatment application thereof | 中国药科大学 | 2024-05-24 | — | — | CN | claimed |
| CN-120483972-B | Quinoline-malononitrile derivative, preparation method thereof and application of quinoline-malononitrile derivative as near-infrared AIE fluorescent probe of targeted lysosome | 烟台大学 | 2025-09-12 | — | — | CN | disclosed |
| CN-120463697-B | Quinoline-malononitrile derivative, preparation method thereof and application of quinoline-malononitrile derivative as near-infrared AIE fluorescent probe targeting COX-2 | 烟台大学 | 2025-09-09 | — | — | CN | disclosed |
| CN-120483972-A | Quinoline-malononitrile derivative, preparation method thereof and application of quinoline-malononitrile derivative as near-infrared AIE fluorescent probe of targeted lysosome | 烟台大学 | 2025-08-15 | — | — | CN | disclosed |
| CN-120463697-A | Quinoline-malononitrile derivative, preparation method thereof and application of quinoline-malononitrile derivative as near-infrared AIE fluorescent probe targeting COX-2 | 烟台大学 | 2025-08-12 | — | — | CN | disclosed |
| CN-115745882-B | Quinoline-malononitrile derivative fluorescent probe and preparation method and application thereof | 东南大学 | 2025-03-25 | — | — | CN | disclosed |
| CN-115745882-B | Quinoline-malononitrile derivative fluorescent probe and preparation method and application thereof | 东南大学 | 2025-03-25 | — | — | CN | disclosed |
| CN-119613394-A | Preparation and application of fluorescent probe for detecting hypochlorous acid | 华中师范大学 | 2025-03-14 | — | — | CN | disclosed |
| CN-119613394-A | Preparation and application of fluorescent probe for detecting hypochlorous acid | 华中师范大学 | 2025-03-14 | — | — | CN | disclosed |
| CN-118059257-A | Preparation method of cathepsin E response preparation and pancreatic cancer specific photodiagnosis and treatment application thereof | 中国药科大学 | 2024-05-24 | — | — | CN | disclosed |
| US-20230321043-A1 | COMPOUNDS HAVING PSEUDOMONAS ANTI-BIOFILM PROPERTIES | UNIV COPENHAGEN (DK) | 2023-10-12 | — | — | US | disclosed |
| US-20230321043-A1 | COMPOUNDS HAVING PSEUDOMONAS ANTI-BIOFILM PROPERTIES | UNIV COPENHAGEN (DK) | 2023-10-12 | — | — | US | disclosed |
| CN-115745882-A | Quinoline-malononitrile derivative fluorescent probe and preparation method and application thereof | 东南大学 | 2023-03-07 | — | — | CN | disclosed |
| CN-115745882-A | Quinoline-malononitrile derivative fluorescent probe and preparation method and application thereof | 东南大学 | 2023-03-07 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230321043-A1 | COMPOUNDS HAVING PSEUDOMONAS ANTI-BIOFILM PROPERTIES | GMPS, PDE11A, CGAS | NCF1 1796/4885CYP1A2 4787/4885NOS2 595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.