Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.51 |
| ▸ | PTGES | O14684 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 11/20 | 0.47 |
| ▸ | CTRC | Q99895 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7784485 | 0.94 | CTRC (0.52) | PPARGALOX5PTGESPPARACTRC | |
| SCHEMBL289442 | 0.87 | PPARG (0.64) | PPARGALOX5PTGESPPARACTRC | |
| SCHEMBL8935884 | 0.87 | PPARG (0.64) | PPARGALOX5PTGESPPARACTRC | |
| SCHEMBL8722173 | 0.84 | PPARG (0.51) | PPARGALOX5PTGESPPARACTRC | |
| SCHEMBL9172839 | 0.83 | ALDH1A1 (0.52) | PPARGPPARATSHRALDH1A1 | |
| SCHEMBL5210592 | 0.83 | TDP1 (0.54) | PPARGALOX5PTGESPPARACTRC | |
| SCHEMBL11858517 | 0.83 | PPARG (0.50) | PPARGALOX5PTGESPPARACTRC | |
| SCHEMBL11403561 | 0.83 | CTRC (0.50) | PPARGALOX5PTGESPPARACTRC | |
| SCHEMBL557511 | 0.82 | CTRC (0.62) | PPARGALOX5PTGESPPARACTRC | |
| SCHEMBL10701164 | 0.81 | PPARG (0.45) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1446110-A2 | ORGANOSULFUR INHIBITORS OF TYROSINE PHOSPHATASES | Structural Bioinformatics Inc. (US) | 2004-08-18 | — | — | EP | disclosed |
| WO-2003032916-A2 | ORGANOSULFUR INHIBITORS OF TYROSINE PHOSPHATASES | STRUCTURAL BIOINFORMATICS INC. (US) | 2003-04-24 | — | — | WO | disclosed |