Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6666784 | 0.93 | POLB (0.32) | ALDH1A1MAPTKDM4E | |
| SCHEMBL6658559 | 0.89 | KDM4E (0.30) | KDM4E | |
| SCHEMBL6660613 | 0.88 | NPY2R (0.35) | ALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL6677369 | 0.88 | RORC (0.31) | — | |
| SCHEMBL6659012 | 0.87 | NPY2R (0.35) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6636214 | 0.86 | ALDH1A1 (0.34) | ALDH1A1PTGESHCRTR2MAPTKDM4E | |
| SCHEMBL6659623 | 0.86 | CYP1A2 (0.42) | ALDH1A1NPSR1KDM4EMEN1KMT2A | |
| SCHEMBL6633734 | 0.86 | ALDH1A1 (0.33) | ALDH1A1PTGESMAPTKDM4EHSP90AA1 | |
| SCHEMBL6684077 | 0.85 | — | — | |
| SCHEMBL6666837 | 0.84 | RAB9A (0.36) | ALDH1A1NPSR1HCRTR2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000051-B1 | CARBAMYLOXY COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARM INC (US) | 2004-05-19 | — | — | EP | claimed |