Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29577405 | 0.88 | LMNA (0.49) | LMNAKMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL6669710 | 0.88 | LMNA (0.49) | LMNAKMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL9321255 | 0.82 | LMNA (0.51) | LMNAKMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL11391125 | 0.81 | ALDH1A1 (0.56) | LMNAKMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL3663507 | 0.81 | KMT2A (0.55) | LMNAKMT2AMAOBALDH1A1MEN1 | |
| SCHEMBL9381103 | 0.81 | LMNA (0.50) | LMNAKMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL5683020 | 0.80 | KDM4E (0.64) | LMNAKMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL11401876 | 0.79 | LMNA (0.61) | LMNAKMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL11389161 | 0.79 | LMNA (0.56) | LMNAKMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL17181494 | 0.78 | LMNA (0.48) | LMNAKMT2AALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0831845-B1 | DIPHOSPHONATE DERIVATIVES OF THERAPEUTIC AGENTS | ELIZANOR BIOPHARMACEUTICALS IN (US) | 2004-09-08 | — | — | EP | disclosed |
| US-5854227-A | Therapeutic derivatives of diphosphonates | ELIZANOR BIOPHARMACUETICALS, INC. | 1998-12-29 | — | — | US | disclosed |
| WO-1996040156-A1 | DIPHOSPHONATE DERIVATIVES OF THERAPEUTIC AGENTS | ELIZANOR BIOPHARMACEUTICALS, INC. (US) | 1996-12-19 | — | — | WO | disclosed |
| US-4292317-A | BACTERICIDES FOR GRAM NEGATIVE AND -POSITIVE BACTERIA; ANIMAL GROWTH REGULATORS | LABORATORIE ROGER BELLON (FR) | 1981-09-29 | — | — | US | disclosed |