SCHEMBL6669710

SCHEMBL6669710

Cn1cc(C(=O)O)c(=O)c2cc(F)c(Cl)cc21

nearest known ligand 0.63

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.49
ALDH1A1 P00352 4/20 0.46
DRD3 P35462 1/20 0.46
KMT2A Q03164 3/20 0.44
MEN1 O00255 2/20 0.43
KDM4E B2RXH2 4/20 0.42
HPGD P15428 2/20 0.42
HSD17B10 Q99714 2/20 0.42
PIM1 P11309 1/20 0.42
BRD4 O60885 1/20 0.42
TSHR P16473 1/20 0.42
HTT P42858 1/20 0.42
CYP2J2 P51589 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
NPC1 O15118 1/20 0.42
GSK3B P49841 1/20 0.41
TOP1 P11387 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29577405 1.00 LMNA (0.49) LMNAALDH1A1DRD3KMT2AMEN1
SCHEMBL9381103 0.88 LMNA (0.50) LMNAALDH1A1DRD3KMT2AMEN1
SCHEMBL6664480 0.88 LMNA (0.53) LMNAALDH1A1DRD3KMT2AMEN1
SCHEMBL14065374 0.84 LMNA (0.47) LMNAALDH1A1DRD3KMT2AMEN1
SCHEMBL10917684 0.83 ALDH1A1 (0.40) LMNAALDH1A1DRD3KMT2AMEN1
SCHEMBL11028522 0.83 ALDH1A1 (0.55) LMNAALDH1A1DRD3KMT2AMEN1
SCHEMBL3816217 0.82 METTL3 (0.44) LMNAALDH1A1DRD3KMT2AMEN1
SCHEMBL29548224 0.82 DRD3 (0.63) LMNAALDH1A1DRD3KMT2AMEN1
SCHEMBL3809668 0.82 DRD3 (0.63) LMNAALDH1A1DRD3KMT2AMEN1
SCHEMBL6212035 0.82 TOP1 (0.41) LMNAALDH1A1DRD3KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250313561-A1 NEXT-GENERATION MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) RYVU THERAPEUTICS S A (PL) 2025-10-09 US disclosed
US-12344606-B2 Next-generation modulators of stimulator of interferon genes (STING) Ryvu Therapeutics S.A. (PL) 2025-07-01 US disclosed
EP-3983078-B1 NEXT-GENERATION MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) RYVU THERAPEUTICS S A (PL) 2023-11-15 EP disclosed
US-20220251082-A1 NEXT-GENERATION MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) Ryvu Therapeutics S.A. (PL) 2022-08-11 US disclosed
EP-3983078-A1 NEXT-GENERATION MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) Ryvu Therapeutics S.A. (PL) 2022-04-20 EP disclosed
CN-113950473-A Next generation modulators of interferon gene Stimulators (STING) 雷沃医疗有限公司 2022-01-18 CN disclosed
WO-2020249773-A1 NEXT-GENERATION MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) Ryvu Therapeutics S.A. (PL) 2020-12-17 WO disclosed
EP-0831845-B1 DIPHOSPHONATE DERIVATIVES OF THERAPEUTIC AGENTS ELIZANOR BIOPHARMACEUTICALS IN (US) 2004-09-08 EP disclosed
US-5854227-A Therapeutic derivatives of diphosphonates ELIZANOR BIOPHARMACUETICALS, INC. 1998-12-29 US disclosed
WO-1996040156-A1 DIPHOSPHONATE DERIVATIVES OF THERAPEUTIC AGENTS ELIZANOR BIOPHARMACEUTICALS, INC. (US) 1996-12-19 WO disclosed
US-4448962-A BACTERICIDES KYORIN SEIYAKU KABUSHIKI KAISHA 1984-05-15 US disclosed
US-4292317-A BACTERICIDES FOR GRAM NEGATIVE AND -POSITIVE BACTERIA; ANIMAL GROWTH REGULATORS LABORATORIE ROGER BELLON (FR) 1981-09-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220251082-A1 NEXT-GENERATION MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) STING1, IRF3, CGAS LMNA 3293/4885ALDH1A1 4562/4885DRD3 3434/4885
US-12344606-B2 Next-generation modulators of stimulator of interferon genes (STING) STING1, IRF3, CGAS LMNA 3293/4885ALDH1A1 4562/4885DRD3 3434/4885
US-20250313561-A1 NEXT-GENERATION MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) STING1, IRF3, CGAS LMNA 3293/4885ALDH1A1 4562/4885DRD3 3434/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.