SCHEMBL6664565

SCHEMBL6664565

O=C(OCc1ccc(F)cc1F)c1ccc(C(=O)OCc2ccc(F)cc2F)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.57
L3MBTL1 Q9Y468 4/20 0.56
POLB P06746 2/20 0.56
IDO1 P14902 2/20 0.53
AGXT P21549 2/20 0.53
NPC1 O15118 2/20 0.49
RAB9A P51151 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
MAPT P10636 2/20 0.49
LMNA P02545 1/20 0.49
HTT P42858 1/20 0.49
TSHR P16473 1/20 0.48
MAPK1 P28482 1/20 0.48
MMP2 P08253 2/20 0.46
MMP12 P39900 2/20 0.46
MMP1 P03956 1/20 0.46
MMP9 P14780 1/20 0.46
GSK3B P49841 1/20 0.46
BACE1 P56817 1/20 0.46
ALDH1A1 P00352 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6668911 0.84 IDO1 (0.58) MAOBL3MBTL1POLBIDO1AGXT
SCHEMBL27997538 0.81 KMT2A (0.57) MAOBL3MBTL1POLBMAPTLMNA
SCHEMBL13034123 0.81 MAOB (0.59) MAOBL3MBTL1POLBIDO1AGXT
SCHEMBL14162423 0.79 MAOB (0.54) MAOBL3MBTL1POLBIDO1AGXT
SCHEMBL28896384 0.79 MMP2 (0.59) L3MBTL1POLBNPC1RAB9ASMN1; SMN2
SCHEMBL721553 0.78 MAOB (0.52) MAOBL3MBTL1POLBIDO1AGXT
SCHEMBL13544370 0.77 MAOB (0.55) MAOBL3MBTL1POLBIDO1AGXT
SCHEMBL3720430 0.76 MAOB (0.50) MAOBL3MBTL1POLBIDO1AGXT
SCHEMBL13292603 0.76 MAOB (0.54) MAOBL3MBTL1POLBIDO1AGXT
SCHEMBL24945950 0.74 MAOB (0.49) MAOBIDO1AGXTMMP2MMP12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1004621-B1 GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME TEIJIN CHEMICALS LTD (JP) 2004-09-15 EP disclosed
US-6485657-B1 Gamma-ray stabilizer and thermoplastic polymer compound including the said stabilizer TEIJIN, LIMITED (JP) 2002-11-26 US disclosed
EP-1004621-A1 GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME TEIJIN LIMITED (JP) 2000-05-31 EP disclosed