Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.59 |
| ▸ | MMP12 | P39900 | 2/20 | 0.59 |
| ▸ | MMP1 | P03956 | 1/20 | 0.59 |
| ▸ | MMP9 | P14780 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27997320 | 0.83 | KMT2A (0.57) | MMP2MMP12MMP1MMP9TDP1 | |
| SCHEMBL6664565 | 0.79 | MAOB (0.57) | MMP2MMP12MMP1MMP9TDP1 | |
| SCHEMBL5085480 | 0.77 | PPARG (0.71) | TDP1SLC6A2SLC6A3KMT2APPARG | |
| SCHEMBL13034155 | 0.77 | MMP2 (0.54) | MMP2MMP12MMP1MMP9LMNA | |
| SCHEMBL28117924 | 0.76 | KMT2A (0.69) | MMP2MMP12MMP1MMP9TDP1 | |
| SCHEMBL28895934 | 0.76 | KMT2A (0.68) | MMP2MMP12MMP1MMP9TDP1 | |
| SCHEMBL6667180 | 0.74 | PPARG (0.58) | TDP1SLC6A2SLC6A3KMT2APPARG | |
| SCHEMBL10611790 | 0.74 | KMT2A (0.56) | TDP1SLC6A2SLC6A3KMT2APPARG | |
| SCHEMBL29083309 | 0.74 | TDP1 (0.56) | MMP2MMP12MMP1MMP9TDP1 | |
| SCHEMBL28758278 | 0.74 | KMT2A (0.66) | TDP1SLC6A2SLC6A3KMT2APPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111995567-B | Formamide pyridone iron chelator derivative with potential multi-target anti-AD activity and preparation method and application thereof | 浙江工业大学 | 2022-11-25 | — | — | CN | disclosed |