SCHEMBL24945950

SCHEMBL24945950

O=C(OCc1ccc(F)cc1F)C(O)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.49
IDO1 P14902 3/20 0.47
AGXT P21549 2/20 0.47
GSK3B P49841 2/20 0.42
BACE1 P56817 2/20 0.42
RIPK1 Q13546 2/20 0.39
ALDH1A1 P00352 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
KDM5A P29375 1/20 0.37
KDM4C Q9H3R0 1/20 0.37
KDM5B Q9UGL1 1/20 0.37
ALKBH1 Q13686 1/20 0.37
MMP2 P08253 2/20 0.36
MMP12 P39900 2/20 0.36
MMP1 P03956 1/20 0.36
MMP9 P14780 1/20 0.36
RORC P51449 1/20 0.36
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24945949 0.88 MMP2 (0.48) MAOBIDO1AGXTRIPK1ALDH1A1
SCHEMBL24901359 0.85 PTGER1 (0.40) TDP1KDM5AKDM5B
SCHEMBL24901418 0.83 MMP2 (0.43) MAOBMMP2MMP12MMP1MMP9
SCHEMBL13544370 0.81 MAOB (0.55) MAOBIDO1AGXTGSK3BBACE1
SCHEMBL24142279 0.81 ALDH1A1 (0.47) MAOBIDO1ALDH1A1TDP1MMP2
SCHEMBL14134236 0.79 RIPK1 (0.58) MAOBIDO1AGXTGSK3BBACE1
SCHEMBL6668911 0.79 IDO1 (0.58) MAOBIDO1AGXTGSK3BBACE1
SCHEMBL24177943 0.78 KMT2A (0.44) MAOBIDO1AGXTMMP2MMP12
SCHEMBL24901410 0.77 MMP2 (0.33) MAOBMMP2MMP12MMP1MMP9
SCHEMBL24142281 0.76 HCAR2 (0.54) MAOBIDO1AGXTMMP2MMP12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230023593-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230023593-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING PROCESS HNRNPU, EWSR1, HNRNPR MAOB 4452/4885IDO1 4664/4885AGXT 2516/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.