Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | ROS1 | P08922 | 1/20 | 0.33 |
| ▸ | MARK3 | P27448 | 1/20 | 0.33 |
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4986865 | 0.74 | SMN1; SMN2 (0.36) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL5370319 | 0.74 | ALDH1A1 (0.35) | KMT2AMEN1ALDH1A1KDM4ELMNA | |
| SCHEMBL2473331 | 0.70 | KMT2A (0.35) | KMT2AMEN1ALDH1A1KDM4EHTR2A | |
| SCHEMBL6339500 | 0.68 | TP53 (0.33) | KMT2AALDH1A1KDM4EGLAGAA | |
| SCHEMBL438926 | 0.68 | HTR2A (0.41) | KMT2AMEN1ALDH1A1KDM4ELMNA | |
| SCHEMBL3214155 | 0.62 | KMT2A (0.49) | KMT2AMEN1LMNAGAAHTR2A | |
| SCHEMBL9739222 | 0.61 | KMT2A (0.36) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL11635434 | 0.61 | KMT2A (0.44) | KMT2AMEN1LMNAHTR2AHTR2C | |
| SCHEMBL11201145 | 0.60 | TSHR (0.47) | KMT2AMEN1ALDH1A1KDM4ELMNA | |
| SCHEMBL13802689 | 0.60 | TP53 (0.36) | KMT2AMEN1ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1270550-B1 | Process for producing 3, 4-Dihydroxybenzonitrile | UBE INDUSTRIES (JP) | 2004-09-15 | — | — | EP | claimed |
| US-6573397-B2 | Chlorinating 3,4-methylenedioxybenzonitrile with sulfuryl chloride or chlorine in presence of promoter to form 2-chloro-benzo(1,3)dioxole-5-carbonitrile, hydrolyzing with water to produce 3,4-dihydroxybenzonitrile | UBE INDUSTRIES, LTD. (JP) | 2003-06-03 | — | — | US | claimed |
| US-20030009048-A1 | Process for producing 3,4-dihydroxybenzonitrile | UBE INDUSTRIES, LTD. | 2003-01-09 | — | — | US | claimed |
| EP-1270550-A1 | Process for producing 3, 4-Dihydroxybenzonitrile | Ube Industries, Ltd. (JP) | 2003-01-02 | — | — | EP | claimed |
| EP-1270550-B1 | Process for producing 3, 4-Dihydroxybenzonitrile | UBE INDUSTRIES (JP) | 2004-09-15 | — | — | EP | disclosed |
| US-6573397-B2 | Chlorinating 3,4-methylenedioxybenzonitrile with sulfuryl chloride or chlorine in presence of promoter to form 2-chloro-benzo(1,3)dioxole-5-carbonitrile, hydrolyzing with water to produce 3,4-dihydroxybenzonitrile | UBE INDUSTRIES, LTD. (JP) | 2003-06-03 | — | — | US | disclosed |
| US-6573397-B2 | Chlorinating 3,4-methylenedioxybenzonitrile with sulfuryl chloride or chlorine in presence of promoter to form 2-chloro-benzo(1,3)dioxole-5-carbonitrile, hydrolyzing with water to produce 3,4-dihydroxybenzonitrile | UBE INDUSTRIES, LTD. (JP) | 2003-06-03 | — | — | US | disclosed |
| US-20030009048-A1 | Process for producing 3,4-dihydroxybenzonitrile | UBE INDUSTRIES, LTD. | 2003-01-09 | — | — | US | disclosed |
| US-20030009048-A1 | Process for producing 3,4-dihydroxybenzonitrile | UBE INDUSTRIES, LTD. | 2003-01-09 | — | — | US | disclosed |
| EP-1270550-A1 | Process for producing 3, 4-Dihydroxybenzonitrile | Ube Industries, Ltd. (JP) | 2003-01-02 | — | — | EP | disclosed |
| EP-1270550-A1 | Process for producing 3, 4-Dihydroxybenzonitrile | Ube Industries, Ltd. (JP) | 2003-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030009048-A1 | Process for producing 3,4-dihydroxybenzonitrile | BPNT1, DCUN1D4, CPN1 | KMT2A 2939/4885MEN1 2481/4885ALDH1A1 1076/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.