Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 5/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | EIF2AK3 | Q9NZJ5 | 4/20 | 0.41 |
| ▸ | SMO | Q99835 | 1/20 | 0.41 |
| ▸ | EIF2AK1 | Q9BQI3 | 2/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | YES1 | P07947 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6809825 | 0.92 | SMO (0.50) | RIPK1SMOMTTPAPOBLMNA | |
| SCHEMBL6665118 | 0.90 | RIPK1 (0.43) | HTR2AHTR2CHTR2BRIPK1EIF2AK3 | |
| Hydrochloric Acid SCHEMBL6666545 | 0.89 | RIPK1 (0.43) | HTR2AHTR2CHTR2BRIPK1EIF2AK3 | |
| SCHEMBL6671845 | 0.89 | CYP11B1 (0.43) | HTR2AHTR2CRIPK1CYP11B1CYP11B2 | |
| SCHEMBL6664848 | 0.89 | HTR2A (0.53) | HTR2AHTR2CHTR2BRIPK1EIF2AK3 | |
| SCHEMBL6669306 | 0.88 | HTR2A (0.40) | HTR2AHTR2CHTR2BRIPK1EIF2AK3 | |
| SCHEMBL6669273 | 0.87 | CYP11B1 (0.44) | RIPK1CYP11B1CYP11B2EIF2AK3EIF2AK1 | |
| SCHEMBL6665703 | 0.86 | CYP11B1 (0.49) | HTR2AHTR2CHTR2BRIPK1CYP11B1 | |
| SCHEMBL6663855 | 0.85 | SRPK1 (0.43) | HTR2AHTR2CHTR2BRIPK1SMO | |
| SCHEMBL6666805 | 0.84 | CASP3 (0.43) | HTR2AHTR2CHTR2BMTTPAPOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383760-A1 | BIARYLCARBOXAMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002090347-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | disclosed |