Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 5/20 | 0.43 |
| ▸ | EIF2AK3 | Q9NZJ5 | 3/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | YES1 | P07947 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.41 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NEK4 | P51957 | 1/20 | 0.41 |
| ▸ | MAP3K9 | P80192 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6666545 | 0.99 | RIPK1 (0.43) | RIPK1EIF2AK3HTR2AHTR2CHTR2B | |
| SCHEMBL6667700 | 0.92 | SMO (0.49) | RIPK1EIF2AK3LMNAMAPTMTTP | |
| Hydrochloric Acid SCHEMBL6805924 | 0.91 | SMO (0.49) | RIPK1EIF2AK3LMNAMAPTMTTP | |
| SCHEMBL6667572 | 0.90 | HTR2A (0.43) | RIPK1EIF2AK3HTR2AHTR2CHTR2B | |
| SCHEMBL6664848 | 0.88 | HTR2A (0.53) | RIPK1EIF2AK3HTR2AHTR2CHTR2B | |
| SCHEMBL6665119 | 0.88 | EIF2AK3 (0.44) | RIPK1EIF2AK3HTR2AHTR2CMAPT | |
| Hydrochloric Acid SCHEMBL6667512 | 0.88 | EIF2AK3 (0.43) | RIPK1EIF2AK3HTR2AHTR2CMAPT | |
| SCHEMBL6666513 | 0.88 | MTTP (0.40) | RIPK1EIF2AK3HTR2AHTR2CHTR2B | |
| SCHEMBL6667216 | 0.87 | RIPK1 (0.44) | RIPK1EIF2AK3HTR2AHTR2CHTR2B | |
| SCHEMBL6666486 | 0.87 | EIF2AK3 (0.41) | RIPK1EIF2AK3EIF2AK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383760-A1 | BIARYLCARBOXAMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-28 | — | — | EP | claimed |
| WO-2002090347-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | claimed |
| EP-1383760-A1 | BIARYLCARBOXAMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002090347-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | disclosed |