Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.63 |
| ▸ | HPGD | P15428 | 8/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.63 |
| ▸ | ACHE | P22303 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 6/20 | 0.44 |
| ▸ | CA9 | Q16790 | 6/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 2/20 | 0.44 |
| ▸ | CASP7 | P55210 | 2/20 | 0.44 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6664850 | 1.00 | ALDH1A1 (0.63) | ALDH1A1KDM4EHPGDHSD17B10ACHE | |
| SCHEMBL12075314 | 0.80 | KDM4E (0.65) | ALDH1A1KDM4EHPGDHSD17B10ACHE | |
| Obliquin SCHEMBL2255488 | 0.77 | KDM4E (1.00) | ALDH1A1KDM4EHPGDHSD17B10ACHE | |
| Obliquin SCHEMBL29534204 | 0.77 | KDM4E (1.00) | ALDH1A1KDM4EHPGDHSD17B10ACHE | |
| Obliquin SCHEMBL12062102 | 0.77 | KDM4E (1.00) | ALDH1A1KDM4EHPGDHSD17B10ACHE | |
| Dihydro-Obliquin SCHEMBL12062091 | 0.77 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDHSD17B10ACHE | |
| SCHEMBL6843275 | 0.75 | KDM4E (0.57) | ALDH1A1KDM4EHPGDHSD17B10ACHE | |
| Ayapin SCHEMBL30171405 | 0.75 | KDM4E (0.57) | ALDH1A1KDM4EHPGDHSD17B10ACHE | |
| Ayapin SCHEMBL6694210 | 0.75 | KDM4E (0.57) | ALDH1A1KDM4EHPGDHSD17B10ACHE | |
| SCHEMBL1044700 | 0.71 | CA2 (0.38) | HPGDCA2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6800768-B1 | STABLE PHOTOACTIVE COUMARIN COMPOUNDS THAT CAN BE USED AS PHOTO-CROSSLINKING REAGENTS IN NUCLEIC ACID HYBRIDIZATION ASSAYS AND THERAPEUTIC APPLICATIONS | NAXCOR, INC. | 2004-10-05 | — | — | US | disclosed |
| WO-2004022703-A2 | NON-NUCLEOSIDIC COUMARIN DERIVATIVES AS POLYNUCLEOTIDE-CROSSLINKING AGENTS | NAXCOR, INC. (US) | 2004-03-18 | — | — | WO | disclosed |
| US-6005093-A | CONMPOUNDS USED AS REPLACEMENTS FOR ONE OR MORE COMPLEMENTARY NUCLEOSIDE BASES IN PROBES; ENABLE PHOTOACTIVE CROSSLINKING OF NUCLEIC ACID STRANDS IN HYBRIDIZATION ASSAYS AND THERAPEUTIC APPLICATIONS | NAXCOR (US) | 1999-12-21 | — | — | US | disclosed |
| EP-0827501-A4 | NON-NUCLEOSIDIC COUMARIN DERIVATIVES AS POLYNUCLEOTIDE-CROSS-LINKING AGENTS | NAXCOR (US) | 1998-06-10 | — | — | EP | disclosed |
| EP-0827501-A1 | NON-NUCLEOSIDIC COUMARIN DERIVATIVES AS POLYNUCLEOTIDE-CROSS-LINKING AGENTS | NAXCOR (US) | 1998-03-11 | — | — | EP | disclosed |
| WO-1996028438-A1 | NON-NUCLEOSIDIC COUMARIN DERIVATIVES AS POLYNUCLEOTIDE-CROSS-LINKING AGENTS | NAXCOR (US) | 1996-09-19 | — | — | WO | disclosed |