Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13462878 | 0.88 | SMN1; SMN2 (0.58) | SMN1; SMN2KMT2ANPC1LMNARAB9A | |
| SCHEMBL3509334 | 0.87 | SMN1; SMN2 (0.54) | SMN1; SMN2KMT2ANPC1LMNARAB9A | |
| SCHEMBL6154283 | 0.83 | KMT2A (0.53) | SMN1; SMN2KMT2ANPC1LMNARAB9A | |
| SCHEMBL9312267 | 0.81 | KMT2A (0.52) | SMN1; SMN2KMT2ANPC1LMNARAB9A | |
| SCHEMBL17438055 | 0.81 | KMT2A (0.52) | SMN1; SMN2KMT2ANPC1LMNARAB9A | |
| SCHEMBL1302838 | 0.81 | SMN1; SMN2 (0.52) | SMN1; SMN2KMT2ANPC1LMNARAB9A | |
| SCHEMBL3510101 | 0.81 | SMN1; SMN2 (0.52) | SMN1; SMN2KMT2ANPC1LMNARAB9A | |
| SCHEMBL12875695 | 0.80 | KMT2A (0.51) | SMN1; SMN2KMT2ANPC1LMNARAB9A | |
| SCHEMBL8573566 | 0.79 | RAB9A (0.50) | SMN1; SMN2KMT2ANPC1LMNARAB9A | |
| SCHEMBL7820902 | 0.79 | RAB9A (0.50) | SMN1; SMN2KMT2ANPC1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1441725-A1 | BENZIMIDAZOLES AND ANALOGUES AND THEIR USE AS PROTEIN KINASES INHIBITORS | Aventis Pharmaceuticals Inc. (US) | 2004-08-04 | — | — | EP | disclosed |
| WO-2003035065-A1 | BENZIMIDAZOLES AND ANALOGUES AND THEIR USE AS PROTEIN KINASES INHIBITORS | AVENTIS PHARMACEUTICALS INC (US) | 2003-05-01 | — | — | WO | disclosed |