Methyleugenol

Methyleugenol

SCHEMBL6664993

C=CCc1ccc(O)c(OC)c1.C=CCc1ccc(OC)c(OC)c1.COC

nearest known ligand 0.88

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.88
ALOX5 P09917 4/20 0.88
PTGS1 P23219 2/20 0.88
CYP3A4 P08684 2/20 0.88
AR P10275 1/20 0.88
TRPM8 Q7Z2W7 1/20 0.88
PPARA Q07869 2/20 0.78
PPARG P37231 2/20 0.78
PPARD Q03181 2/20 0.78
GABRA1 P14867 4/20 0.68
GABRB2 P47870 4/20 0.68
MEN1 O00255 3/20 0.61
KMT2A Q03164 3/20 0.61
SMN1; SMN2 Q16637 2/20 0.61
KDM4E B2RXH2 2/20 0.61
GAA P10253 2/20 0.61
MAPT P10636 2/20 0.61
LMNA P02545 1/20 0.61
HTT P42858 1/20 0.61
CNR2 P34972 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyleugenol SCHEMBL28528099 1.00 ALDH1A1 (0.88) ALDH1A1ALOX5PTGS1CYP3A4AR
Methyleugenol SCHEMBL5689919 0.98 ALDH1A1 (0.90) ALDH1A1ALOX5PTGS1CYP3A4AR
Eugenol SCHEMBL5689917 0.95 ALDH1A1 (0.97) ALDH1A1ALOX5PTGS1CYP3A4AR
Eugenol SCHEMBL219169 0.95 ALDH1A1 (0.97) ALDH1A1ALOX5PTGS1CYP3A4AR
Eugenol SCHEMBL28148747 0.94 ALDH1A1 (0.93) ALDH1A1ALOX5PTGS1CYP3A4AR
Eugenol SCHEMBL29364978 0.94 ALDH1A1 (1.00) ALDH1A1ALOX5PTGS1CYP3A4AR
Eugenol SCHEMBL29126189 0.94 ALDH1A1 (1.00) ALDH1A1ALOX5PTGS1CYP3A4AR
Eugenol SCHEMBL20361 0.94 ALDH1A1 (1.00) ALDH1A1ALOX5PTGS1CYP3A4AR
Eugenol SCHEMBL788240 0.94 ALDH1A1 (1.00) ALDH1A1ALOX5PTGS1CYP3A4AR
Eugenol SCHEMBL15756395 0.93 ALOX5 (0.80) ALDH1A1ALOX5PTGS1CYP3A4AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1448573-A1 PROMOTED HYDROSILATION REACTIONS GENERAL ELECTRIC COMPANY (US) 2004-08-25 EP disclosed
WO-2003044028-A1 PROMOTED HYDROSILATION REACTIONS GENERAL ELECTRIC COMPANY (US) 2003-05-30 WO disclosed