Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK3 | Q9NZJ5 | 4/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6667512 | 0.99 | EIF2AK3 (0.43) | EIF2AK3RIPK1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL6803357 | 0.91 | EIF2AK3 (0.46) | EIF2AK3RIPK1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL6666486 | 0.91 | EIF2AK3 (0.41) | EIF2AK3RIPK1MAPTSMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL6804708 | 0.91 | EIF2AK3 (0.45) | EIF2AK3RIPK1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL6662998 | 0.90 | EIF2AK3 (0.42) | EIF2AK3RIPK1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL6667819 | 0.90 | EIF2AK3 (0.41) | EIF2AK3RIPK1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL6800936 | 0.90 | EIF2AK3 (0.46) | EIF2AK3RIPK1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL6671845 | 0.89 | CYP11B1 (0.43) | EIF2AK3RIPK1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL6665118 | 0.88 | RIPK1 (0.43) | EIF2AK3RIPK1MAPTHTR2AHTR2C | |
| SCHEMBL6665768 | 0.88 | MAPT (0.41) | EIF2AK3RIPK1MAPTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383760-A1 | BIARYLCARBOXAMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-28 | — | — | EP | claimed |
| WO-2002090347-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | claimed |
| EP-1383760-A1 | BIARYLCARBOXAMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002090347-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | disclosed |