SCHEMBL6665133

SCHEMBL6665133

CCCc1ccc(C(F)(F)OC(C)c2ccc(F)c(F)c2)cc1

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34
MAPT P10636 1/20 0.34
HTT P42858 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
KMT2A Q03164 2/20 0.33
KCNH2 Q12809 1/20 0.33
TMEM97 Q5BJF2 1/20 0.33
AKR1C3 P42330 1/20 0.32
AKR1C2 P52895 1/20 0.32
MEN1 O00255 1/20 0.32
PDE2A O00408 1/20 0.31
CASR P41180 1/20 0.31
DPP4 P27487 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31
PDPK1 O15530 1/20 0.31
ACACB O00763 1/20 0.31
ACACA Q13085 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6663948 0.91 HTR2A (0.37) ALDH1A1
SCHEMBL6664134 0.89 ALDH1A1 (0.35) ALDH1A1L3MBTL1AKR1C3AKR1C2PDE2A
SCHEMBL6662181 0.89 KMT2A (0.33) MAPTKMT2AKCNH2TMEM97AKR1C3
SCHEMBL6667147 0.89 FFAR1 (0.37) KMT2AAKR1C3AKR1C2MEN1PDE2A
SCHEMBL6661128 0.87 KMT2A (0.36) ALDH1A1KMT2AKCNH2TMEM97MEN1
SCHEMBL6666741 0.87 PDE2A (0.43) PDE2ACASR
SCHEMBL6665748 0.86 TAAR1 (0.33) ALDH1A1MAPTKMT2AKCNH2TMEM97
SCHEMBL6661249 0.86 KDM4E (0.38) ALDH1A1L3MBTL1
SCHEMBL6662000 0.86 PDE2A (0.35) PDE2ACASR
SCHEMBL6661144 0.85 KMT2A (0.43) ALDH1A1MAPTHTTL3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0893423-B1 LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED LINKAGES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES CHISSO CORP (JP) 2004-09-01 EP disclosed