SCHEMBL6665748

SCHEMBL6665748

CCCc1ccc(C(F)(F)OC(C)c2cc(F)c(C(F)(F)F)c(F)c2)cc1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
CASR P41180 4/20 0.33
PSMB5 P28074 1/20 0.32
KCNH2 Q12809 1/20 0.32
TMEM97 Q5BJF2 1/20 0.32
AKR1C3 P42330 1/20 0.32
AKR1C2 P52895 1/20 0.32
SIGMAR1 Q99720 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
ADRA2C P18825 1/20 0.32
HTR2A P28223 1/20 0.32
SLC6A4 P31645 1/20 0.32
ADRA1A P35348 1/20 0.32
DRD3 P35462 1/20 0.32
OPRK1 P41145 1/20 0.32
HTR2B P41595 1/20 0.32
PDE2A O00408 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6661194 0.91 HTR2A (0.36) LMNAADRA2CHTR2ASLC6A4ALDH1A1
SCHEMBL6662181 0.91 KMT2A (0.33) TAAR1MEN1KMT2ACASRPSMB5
SCHEMBL6662051 0.90 CASR (0.34) CASRAKR1C3AKR1C2SIGMAR1LMNA
SCHEMBL6665133 0.86 ALDH1A1 (0.34) TAAR1MEN1KMT2ACASRKCNH2
SCHEMBL6663207 0.85 MEN1 (0.32) MEN1KMT2ACASR
SCHEMBL6667147 0.85 FFAR1 (0.37) TAAR1MEN1KMT2APSMB5AKR1C3
SCHEMBL6666040 0.84 ALDH1A1 (0.33) MEN1KMT2AMAPTALDH1A1
SCHEMBL6664038 0.84
SCHEMBL6661128 0.83 KMT2A (0.36) TAAR1MEN1KMT2APSMB5KCNH2
SCHEMBL6660765 0.82 MEN1 (0.42) TAAR1MEN1KMT2APSMB5KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0893423-B1 LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED LINKAGES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES CHISSO CORP (JP) 2004-09-01 EP disclosed