SCHEMBL6667147

SCHEMBL6667147

CCCc1ccc(C(F)(F)OC(C)c2ccc(C(F)(F)F)c(F)c2)cc1

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.37
KIF11 P52732 1/20 0.35
DAO P14920 1/20 0.35
PSMB5 P28074 1/20 0.33
AKR1C3 P42330 2/20 0.33
AKR1C2 P52895 2/20 0.33
PDE2A O00408 6/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
PPARG P37231 1/20 0.32
TRPM8 Q7Z2W7 1/20 0.32
TAAR1 Q96RJ0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6666303 0.92 TRPV1 (0.36) FFAR1KIF11DAO
SCHEMBL6667081 0.90 FFAR1 (0.38) FFAR1KIF11DAOAKR1C3AKR1C2
SCHEMBL6665133 0.89 ALDH1A1 (0.34) AKR1C3AKR1C2PDE2AMEN1KMT2A
SCHEMBL6662181 0.86 KMT2A (0.33) PSMB5AKR1C3AKR1C2MEN1KMT2A
SCHEMBL6665748 0.85 TAAR1 (0.33) PSMB5AKR1C3AKR1C2PDE2AMEN1
SCHEMBL6661128 0.84 KMT2A (0.36) KIF11PSMB5PDE2AMEN1KMT2A
SCHEMBL6666741 0.83 PDE2A (0.43) PDE2A
SCHEMBL6660765 0.83 MEN1 (0.42) PSMB5PDE2AMEN1KMT2APPARG
SCHEMBL6662000 0.82 PDE2A (0.35) PDE2A
SCHEMBL6661249 0.82 KDM4E (0.38) DAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0893423-B1 LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED LINKAGES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES CHISSO CORP (JP) 2004-09-01 EP disclosed