Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORT1 | Q99523 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | SRPK1 | Q96SB4 | 9/20 | 0.39 |
| ▸ | SMO | Q99835 | 2/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | LPL | P06858 | 1/20 | 0.38 |
| ▸ | LIPC | P11150 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | MTTP | P55157 | 2/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
| ▸ | APOB | P04114 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6801395 | 0.92 | SMO (0.47) | HRH1HTR6SRPK1SMOHTR2A | |
| SCHEMBL6667054 | 0.87 | SORT1 (0.40) | SORT1SRPK1SMONTRK1LPL | |
| SCHEMBL6666524 | 0.82 | SMO (0.51) | SORT1SRPK1SMOLPLLIPC | |
| SCHEMBL6666013 | 0.82 | SMO (0.51) | SORT1SRPK1SMOHTR2AHTR2C | |
| SCHEMBL6663843 | 0.81 | NOTUM (0.44) | MTTPTRPV4APOB | |
| SCHEMBL6642755 | 0.79 | SMO (0.49) | SORT1SRPK1SMOLPLLIPC | |
| SCHEMBL6803527 | 0.78 | SMO (0.47) | SRPK1SMOHTR2AHTR2CHTR2B | |
| SCHEMBL6666569 | 0.74 | SMO (0.44) | SRPK1SMOHTR2AHTR2CHTR2B | |
| SCHEMBL6667845 | 0.74 | SRPK1 (0.44) | SORT1SRPK1SMOHTR2AHTR2C | |
| SCHEMBL6669784 | 0.74 | SMO (0.53) | SORT1SRPK1SMOHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383760-A1 | BIARYLCARBOXAMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002090347-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | disclosed |