Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MTTP | P55157 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.37 |
| ▸ | APOB | P04114 | 2/20 | 0.37 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6800720 | 0.91 | KDM4E (0.47) | NOTUMKMT2AMTTPKDM4EAPOB | |
| SCHEMBL6667054 | 0.86 | SORT1 (0.40) | — | |
| SCHEMBL6665293 | 0.81 | SORT1 (0.40) | MTTPAPOBTRPV4 | |
| SCHEMBL6669985 | 0.80 | PARP10 (0.40) | MTTPAPOBHCRTR1HCRTR2FABP4 | |
| SCHEMBL6667492 | 0.79 | NOTUM (0.60) | NOTUMTSHRMTTPAPOBUSP2 | |
| SCHEMBL5111860 | 0.76 | MTTP (0.40) | TSHRMEN1POLBKMT2AMTTP | |
| SCHEMBL6801395 | 0.71 | SMO (0.47) | MTTPKDM4EAPOBLMNAGAA | |
| SCHEMBL14288688 | 0.70 | MTTP (0.52) | KMT2AMTTPKDM4EAPOBLMNA | |
| SCHEMBL6809331 | 0.69 | MTTP (0.46) | MTTPKDM4EAPOBGAA | |
| SCHEMBL6804769 | 0.69 | MTTP (0.62) | NOTUMMTTPKDM4EAPOBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383760-A1 | BIARYLCARBOXAMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002090347-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | disclosed |