Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.48 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6665446 | 1.00 | ACE (0.52) | ACEACE2ALDH1A1HSD17B10LMNA | |
| SCHEMBL26079422 | 0.83 | LMNA (0.56) | ACEACE2ALDH1A1HSD17B10LMNA | |
| SCHEMBL6429637 | 0.82 | FKBP1A (0.67) | ACEACE2ALDH1A1HSD17B10ITGB1 | |
| SCHEMBL7066815 | 0.81 | FKBP1A (0.61) | ACEACE2ALDH1A1HSD17B10LMNA | |
| SCHEMBL29413761 | 0.80 | ALDH1A1 (0.61) | ACEACE2ALDH1A1HSD17B10LMNA | |
| SCHEMBL6369038 | 0.79 | ITGB1 (0.54) | ACEALDH1A1HSD17B10LMNATDP1 | |
| SCHEMBL7707493 | 0.79 | ITGB1 (0.60) | ALDH1A1HSD17B10LMNATDP1ITGB1 | |
| SCHEMBL30468238 | 0.79 | SLC6A2 (0.56) | F2PLG | |
| SCHEMBL7066929 | 0.78 | ITGB1 (0.61) | ACEALDH1A1HSD17B10LMNATDP1 | |
| SCHEMBL27538863 | 0.78 | ITGB1 (0.61) | ACEALDH1A1HSD17B10LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8325131-A | — | — | None | — | — | JP | disclosed |
| JP-2004339241-A | COSMETIC | KYOWA HAKKO KOGYO CO LTD | 2004-12-02 | — | — | JP | disclosed |
| JP-H08325131-A | COSMETIC | KYOWA HAKKO KOGYO CO LTD | 1996-12-10 | — | — | JP | disclosed |