Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBFB | Q13951 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | KIF20B | Q96Q89 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | GLP1R | P43220 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
| ▸ | JUN | P05412 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12495589 | 0.81 | CACNA1H (0.46) | EGLN1CACNA1HCACNA1BCACNA1C | |
| SCHEMBL27672328 | 0.81 | CACNA1H (0.35) | CACNA1HCACNA1BCACNA1CMETAP2 | |
| SCHEMBL6667903 | 0.79 | RIPK1 (0.42) | EGLN1CACNA1HCACNA1BCACNA1CMETAP2 | |
| SCHEMBL8564324 | 0.76 | HTT (0.44) | CBFBEGLN1ALDH1A1KDM4E | |
| SCHEMBL18894088 | 0.73 | NOTUM (0.31) | — | |
| SCHEMBL15939046 | 0.73 | ALDH1A1 (0.36) | CACNA1HALDH1A1CACNA1BCACNA1C | |
| SCHEMBL31023736 | 0.70 | CBFB (0.43) | CBFBEGLN1KIF20BCACNA1HALDH1A1 | |
| SCHEMBL13898334 | 0.70 | CBFB (0.46) | CBFBEGLN1KIF20BALDH1A1PLAU | |
| SCHEMBL1193064 | 0.70 | CBFB (0.56) | CBFBEGLN1KIF20BCACNA1HCACNA1B | |
| SCHEMBL1246822 | 0.68 | NPBWR1 (0.44) | CBFBKDM4EMETAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1871232-A | Benzimidazolyl derivatives | MERCK PATENT GMBH (DE) | 2006-11-29 | — | — | CN | claimed |
| CN-1871232-A | Benzimidazolyl derivatives | MERCK PATENT GMBH (DE) | 2006-11-29 | — | — | CN | disclosed |
| EP-1141021-B1 | REMOVAL/PURIFICATION OF SERUM ALBUMINS | AMERSHAM BIOSCIENCES AB (SE) | 2004-09-08 | — | — | EP | disclosed |