Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 7/20 | 0.47 |
| ▸ | HTR2B | P41595 | 7/20 | 0.47 |
| ▸ | HTR2A | P28223 | 6/20 | 0.47 |
| ▸ | EIF2AK3 | Q9NZJ5 | 2/20 | 0.45 |
| ▸ | SMO | Q99835 | 3/20 | 0.44 |
| ▸ | MTTP | P55157 | 2/20 | 0.44 |
| ▸ | APOB | P04114 | 1/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6667820 | 0.92 | SMO (0.50) | HTR2CHTR2BHTR2AEIF2AK3SMO | |
| SCHEMBL6664967 | 0.89 | HTR2A (0.46) | HTR2CHTR2BHTR2AEIF2AK3SMO | |
| SCHEMBL6668416 | 0.89 | HTR2C (0.49) | HTR2CHTR2BHTR2AEIF2AK3SMO | |
| SCHEMBL6668308 | 0.88 | HTR2C (0.45) | HTR2CHTR2BHTR2AEIF2AK3SMO | |
| SCHEMBL6664848 | 0.87 | HTR2A (0.53) | HTR2CHTR2BHTR2AEIF2AK3SMO | |
| SCHEMBL6662151 | 0.85 | HTR2A (0.48) | HTR2CHTR2BHTR2AEIF2AK3SMO | |
| SCHEMBL6646377 | 0.84 | HTR2A (0.55) | HTR2CHTR2BHTR2AEIF2AK3SMO | |
| SCHEMBL6801694 | 0.84 | MTTP (0.64) | SMOMTTPAPOB | |
| SCHEMBL6803761 | 0.84 | MTTP (0.55) | HTR2CHTR2BHTR2AEIF2AK3SMO | |
| SCHEMBL6805171 | 0.83 | SMO (0.52) | HTR2CHTR2BHTR2AEIF2AK3SMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383760-A1 | BIARYLCARBOXAMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002090347-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | disclosed |