Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | ESR1 | P03372 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29776988 | 0.81 | POLB (0.62) | MEN1ESR1KMT2AESR2ATM | |
| SCHEMBL6912873 | 0.81 | POLB (0.62) | MEN1ESR1KMT2AESR2ATM | |
| SCHEMBL11856777 | 0.81 | MEN1 (0.58) | MEN1ESR1KMT2AESR2ATM | |
| SCHEMBL8761644 | 0.80 | HTR6 (0.49) | MEN1ESR1KMT2AESR2ATM | |
| Hydrochloric Acid SCHEMBL27436292 | 0.79 | MEN1 (0.52) | MEN1ESR1KMT2AESR2ATM | |
| SCHEMBL8761703 | 0.79 | MAOB (0.45) | MEN1KMT2AATMALDH1A1CYP3A4 | |
| SCHEMBL29673555 | 0.78 | LMNA (0.49) | MEN1KMT2AALDH1A1CYP3A4MAOB | |
| SCHEMBL22187461 | 0.78 | LMNA (0.49) | MEN1KMT2AALDH1A1CYP3A4MAOB | |
| SCHEMBL6666074 | 0.77 | ALDH1A1 (0.55) | POLBALDH1A1CYP3A4MAOBCA1 | |
| SCHEMBL29673592 | 0.77 | ALDH1A1 (0.55) | POLBALDH1A1CYP3A4MAOBCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140515-B1 | HEAT SENSITIVE RECORDING MATERIAL | CIBA SC HOLDING AG (CH) | 2004-09-15 | — | — | EP | disclosed |
| US-6624117-B1 | Heat sensitive recording material | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-09-23 | — | — | US | disclosed |
| EP-1140515-A1 | HEAT SENSITIVE RECORDING MATERIAL | Ciba SC Holding AG (CH) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035679-A1 | HEAT SENSITIVE RECORDING MATERIAL | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-06-22 | — | — | WO | disclosed |