SCHEMBL666720

SCHEMBL666720

Clc1ccc(N(c2ccc(Cl)cc2)c2ccc(Cl)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.57
CYP2A6 P11509 1/20 0.57
ENPP2 Q13822 1/20 0.43
IDO1 P14902 2/20 0.42
TSHR P16473 4/20 0.41
TDP1 Q9NUW8 3/20 0.41
MAPK1 P28482 3/20 0.41
HIF1A Q16665 1/20 0.41
ALDH1A1 P00352 4/20 0.41
KDM4E B2RXH2 2/20 0.41
HSD17B10 Q99714 2/20 0.41
ALOX15 P16050 2/20 0.41
HPGD P15428 1/20 0.41
CYP3A4 P08684 4/20 0.39
CYP1A2 P05177 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
CYP2D6 P10635 1/20 0.39
MAPT P10636 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9162009 0.91 CYP1A2 (0.52) LMNACYP2A6ENPP2IDO1TSHR
SCHEMBL22182575 0.91 CYP1A2 (0.52) LMNACYP2A6ENPP2IDO1TSHR
SCHEMBL1133413 0.88 ALDH1A1 (0.56) LMNACYP2A6TSHRTDP1ALDH1A1
SCHEMBL3419224 0.88 ALDH1A1 (0.56) LMNACYP2A6TSHRTDP1ALDH1A1
SCHEMBL6350639 0.88 ALDH1A1 (0.56) LMNACYP2A6TSHRTDP1ALDH1A1
SCHEMBL13050042 0.88 ALDH1A1 (0.56) LMNACYP2A6TSHRTDP1ALDH1A1
SCHEMBL6353251 0.86 CES2 (0.48) LMNACYP2A6TSHRTDP1ALDH1A1
Hydrochloric Acid SCHEMBL29208948 0.86 ALDH1A1 (0.54) LMNACYP2A6IDO1TSHRTDP1
SCHEMBL21632449 0.86 CYP2A6 (0.42) LMNACYP2A6ENPP2TSHRTDP1
SCHEMBL14832517 0.86 MAPK1 (0.50) LMNACYP2A6ENPP2TDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115433364-A Hydrogen bond organic molecular framework material HOF-NBDA and preparation method and application thereof 中国科学院福建物质结构研究所 2022-12-06 CN claimed
CN-112724373-B Functional organic porous polymer and preparation method and application thereof 山东大学 2021-09-21 CN claimed
CN-112724373-A Functional organic porous polymer and preparation method and application thereof 山东大学 2021-04-30 CN claimed
WO-2001068740-A1 CHARGE TRANSPORT MATERIALS AVECIA LIMITED (GB) 2001-09-20 WO claimed
US-5999780-A Controllably conductive polymer compositions for development systems XEROX CORPORATION (US) 1999-12-07 US claimed
US-5834080-A Controllably conductive polymer compositions for development systems XEROX CORPORATION (US) 1998-11-10 US claimed
US-4954665-A ETHANOL FROM METHANOL AND SYSTHESIS GAS UNION CARBIDE CHEMICALS AND PLASTICS COMPANY INC. (US) 1990-09-04 US claimed
CN-115505103-B Conjugated microporous polymer, organic amine catalytic synthesis method and application thereof 华中科技大学 2024-06-28 CN disclosed
CN-114341104-B Dopant and conductive composition, and method for producing same 国立大学法人东京大学 2024-03-15 CN disclosed
CN-115433364-B Hydrogen bond organic molecular framework material HOF-NBDA, and preparation method and application thereof 中国科学院福建物质结构研究所 2023-09-08 CN disclosed
CN-115505103-A Conjugated microporous polymer, and organic amine catalytic synthesis method and application thereof 华中科技大学 2022-12-23 CN disclosed
CN-115433364-A Hydrogen bond organic molecular framework material HOF-NBDA and preparation method and application thereof 中国科学院福建物质结构研究所 2022-12-06 CN disclosed
CN-114341104-A Dopant and conductive composition and method for producing the same 国立大学法人东京大学 2022-04-12 CN disclosed
EP-0144936-A2 Production of carboxylic acids from alcohols UNION CARBIDE CORPORATION (US) 1985-06-19 EP disclosed
WO-1985002400-A1 PROCESS FOR PRODUCING ORGANIC ACIDS UNION CARBIDE CORPORATION (US) 1985-06-06 WO disclosed
US-4513151-A Acetaldehyde process UNION CARBIDE CORPORATION (US) 1985-04-23 US disclosed
US-4511741-A COBALT AND RHODIUM CATALYST, LITHIUM HALIDE PROMOTER UNION CARBIDE CORPORATION (US) 1985-04-16 US disclosed
US-4447648-A USING SYNTHESIS GAS AND A GROUP VIII COMPOUND UNION CARBIDE CORPORATION (US) 1984-05-08 US disclosed
US-4429165-A TRIVALENT ORGANOPHOSPHORUS AND ORGANONITROGEN COMPOUNDS AS PROMOTERS UNION CARBIDE CORPORATION (US) 1984-01-31 US disclosed
US-4144260-A Production of aluminum salts of N-nitroso-N-alkyl-hydroxylamines BASF AKTIENGESELLSCHAFT (DE) 1979-03-13 US disclosed