Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | GPR18 | Q14330 | 1/20 | 0.34 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6678529 | 0.80 | ALDH1A1 (0.37) | P2RX3ALDH1A1TSHRL3MBTL1PTGDR2 | |
| SCHEMBL6663839 | 0.79 | ALDH1A1 (0.36) | P2RX3ALDH1A1TSHRL3MBTL1PTGDR2 | |
| SCHEMBL6680997 | 0.72 | S1PR1 (0.38) | P2RX3ALDH1A1TSHRL3MBTL1PTGDR2 | |
| SCHEMBL6700331 | 0.70 | TRPC5 (0.38) | P2RX3PTGDR2GRIN1GRIN2BDPP4 | |
| SCHEMBL6699400 | 0.70 | PTGS1 (0.40) | PTGDR2GRIN1GRIN2BDPP4PTGS1 | |
| SCHEMBL6703224 | 0.70 | PTGS1 (0.41) | PTGDR2GRIN1GRIN2BPTGS1PTGS2 | |
| SCHEMBL6702361 | 0.69 | NPSR1 (0.43) | ALDH1A1PTGDR2GRIN1GRIN2BDPP4 | |
| SCHEMBL6703218 | 0.69 | NPSR1 (0.39) | P2RX3PTGDR2GRIN1GRIN2BDPP4 | |
| SCHEMBL6705127 | 0.69 | PTGS1 (0.38) | P2RX3ALDH1A1TSHRL3MBTL1PTGDR2 | |
| SCHEMBL6466057 | 0.68 | MMP13 (0.57) | PTGDR2PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014921-A1 | 5,6-FUSED URACIL DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | disclosed |