SCHEMBL6667487

SCHEMBL6667487

N#Cc1cccc(OC(=O)O)c1

nearest known ligand 0.52

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 13/20 0.52
PRSS1 P07477 1/20 0.52
ACR P10323 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.46
GSK3B P49841 2/20 0.45
FFAR1 O14842 1/20 0.44
FFAR4 Q5NUL3 1/20 0.44
XDH P47989 1/20 0.44
SLC22A12 Q96S37 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18917202 0.90 XDH (0.54) MGLLPRSS1ACRXDHSLC22A12
SCHEMBL10547627 0.87 CYP3A4 (0.58) MGLLPRSS1ACRSMN1; SMN2
SCHEMBL30676498 0.87 CYP3A4 (0.58) MGLLPRSS1ACRSMN1; SMN2
SCHEMBL8580189 0.87 MGLL (0.54) MGLLPRSS1ACRGSK3B
SCHEMBL6667481 0.85 MGLL (0.52) MGLLPRSS1ACRSMN1; SMN2GSK3B
SCHEMBL16439785 0.84 MGLL (0.51) MGLLPRSS1ACRSMN1; SMN2GSK3B
SCHEMBL27811220 0.84 MEN1 (0.66) MGLLPRSS1ACRGSK3B
SCHEMBL17460125 0.84 MGLL (0.51) MGLLPRSS1ACRSMN1; SMN2GSK3B
SCHEMBL28741088 0.83 PRSS1 (0.65) MGLLPRSS1ACRGSK3B
SCHEMBL28577855 0.82 MGLL (0.50) MGLLPRSS1ACRSMN1; SMN2GSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0772087-B1 Pyrazolylazophenol dye FUJI PHOTO FILM CO LTD (JP) 2004-09-08 EP disclosed
US-6495304-B2 NOVEL COLOR-DEVELOPING AGENT OF A 1,2,4- THIADIAZOL-5-YL HYDRAZINE TYPE FUJI PHOTO FILM CO., LTD. (JP) 2002-12-17 US disclosed
US-20020102489-A1 Color-developing agent, silver halide photographic light-sensitive material and image-forming method FUJIFILM CORPORATION (JP) 2002-08-01 US disclosed
EP-0903633-B1 Heat-developable color light-sensitive material FUJI PHOTO FILM CO LTD (JP) 2002-07-24 EP disclosed
US-6352821-B1 DEVELOPING SILVER HALIDE COLOR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL, SUPPLYING ACIDIC SOLUTION HAVING PH OF 4 OR LESS, IN FORM OF THIN LAYER, ONTO LIGHT-SENSITIVE MATERIAL, SO AS TO HAVE SPECIFIED COVERAGE FUJI PHOTO FILM CO., LTD. (JP) 2002-03-05 US disclosed
EP-0715209-B1 Heat-developable color light-sensitive material FUJI PHOTO FILM CO LTD (JP) 2002-02-13 EP disclosed
US-6277994-B1 IMAGE QUALITY AND IMAGE STORABILITY FUJI PHOTO FILM CO., LTD. (JP) 2001-08-21 US disclosed
US-6127088-A IMAGE-FORMING PROCESS COMPRISING HEATING HEAT DEVELOPABLE COLOR LIGHT-SENSITIVE MATERIAL WITH OR AFTER IMAGEWISE EXPOSURE, SAID MATERIAL COMPRISING SUPPORT BEARING SILVER HALIDE EMULSION LAYER AND CONTAINING SPECIFIED DYE PRECURSOR FUJI PHOTO FILM CO., LTD. (JP) 2000-10-03 US disclosed
US-6124084-A AZO DYES; GOOD FASTNESS TO COLOR, HUMIDITY AND HEAT FUJI PHOTO FILM CO., LTD. (JP) 2000-09-26 US disclosed
EP-0620491-B1 Heat developable color light-sensitive material FUJI PHOTO FILM CO LTD (JP) 1999-12-15 EP disclosed
US-5543279-A SMALL FLUCTUATION IN SENSITIVITY WITH TEMPERATURE CHANGE FUJI PHOTO FILM CO., LTD. (JP) 1996-08-06 US disclosed
EP-0715209-A2 Heat-developable color light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1996-06-05 EP disclosed
US-5503969-A COMPRISING AN ALKYLESTERALKYLCARBOXYLIC ACID ANTIFOGGING AGENT FUJI PHOTO FILM CO., LTD. (JP) 1996-04-02 US disclosed
EP-0426112-B1 Silver halide photographic material FUJI PHOTO FILM CO LTD (JP) 1996-02-28 EP disclosed
EP-0620490-A1 Silver halide light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1994-10-19 EP disclosed
EP-0620491-A1 Heat developable color light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1994-10-19 EP disclosed
US-5151357-A Light sensitive elements with phosphonate groups FUJI PHOTO FILM CO., LTD. (JP) 1992-09-29 US disclosed
US-5075208-A Releasing a photographically useful compound upon reduction FUJI PHOTO FILM CO., LTD. (JP) 1991-12-24 US disclosed
US-4994363-A Silver halide light-sensitive material containing a compound releasing a photographically useful group FUJI PHOTO FILM CO., LTD. (JP) 1991-02-19 US disclosed
US-4840887-A USEFUL GROUP RELEASED BY CLEAVAGE BETWEEN SULFONYL GROUP AND A NITROGEN, SULFUR OR OXYGEN ATOM; STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1989-06-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020102489-A1 Color-developing agent, silver halide photographic light-sensitive material and image-forming method SHH, GLI1, HELZ MGLL 2771/4885PRSS1 3620/4885ACR 1445/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.