SCHEMBL6667665

SCHEMBL6667665

Cc1ccc(COC(=O)C2CCCC(C(=O)OCc3ccc(C)cc3C)C2)c(C)c1

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.51
ALDH1A1 P00352 6/20 0.45
POLB P06746 1/20 0.43
LMNA P02545 2/20 0.42
NPSR1 Q6W5P4 1/20 0.42
HPGD P15428 3/20 0.40
MEN1 O00255 1/20 0.40
RAB9A P51151 1/20 0.40
KMT2A Q03164 1/20 0.40
SMN1; SMN2 Q16637 3/20 0.39
GAA P10253 1/20 0.38
MDM2 Q00987 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6669050 0.88 KDM4E (0.52) KDM4EALDH1A1POLBLMNANPSR1
SCHEMBL6666366 0.78 GAA (0.47) KDM4EALDH1A1POLBNPSR1MEN1
SCHEMBL21896024 0.76 KCNQ3 (0.48) KDM4EALDH1A1LMNANPSR1HPGD
SCHEMBL6667424 0.75 SMN1; SMN2 (0.50) KDM4EALDH1A1LMNAMEN1RAB9A
SCHEMBL21895664 0.74 ALDH1A1 (0.44) KDM4EALDH1A1POLBLMNAHPGD
SCHEMBL4316026 0.74 ALDH1A1 (0.54) KDM4EALDH1A1LMNAMEN1RAB9A
SCHEMBL11467418 0.74 SMN1; SMN2 (0.49) KDM4EALDH1A1LMNAMEN1RAB9A
SCHEMBL6672170 0.72 ALDH1A1 (0.43) KDM4EALDH1A1POLBNPSR1HPGD
SCHEMBL20738248 0.71 KDM4E (0.50) KDM4EALDH1A1LMNANPSR1HPGD
SCHEMBL13686678 0.70 ALDH1A1 (0.49) KDM4EALDH1A1POLBLMNANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1004621-B1 GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME TEIJIN CHEMICALS LTD (JP) 2004-09-15 EP disclosed
US-6485657-B1 Gamma-ray stabilizer and thermoplastic polymer compound including the said stabilizer TEIJIN, LIMITED (JP) 2002-11-26 US disclosed
EP-1004621-A1 GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME TEIJIN LIMITED (JP) 2000-05-31 EP disclosed