Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | EDNRB | P24530 | 1/20 | 0.62 |
| ▸ | EDNRA | P25101 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | PFKFB3 | Q16875 | 2/20 | 0.48 |
| ▸ | PPIA | P62937 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | PFKFB4 | Q16877 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19334485 | 0.79 | KMT2A (0.59) | TSHRMAPK1MAPTPPIAALDH1A1 | |
| SCHEMBL4631390 | 0.79 | EDNRA (0.78) | EDNRBEDNRA | |
| SCHEMBL23440311 | 0.77 | TSHR (0.80) | TSHRMAPK1EDNRBEDNRAMAPT | |
| SCHEMBL6664966 | 0.77 | PFKFB4 (0.49) | TSHRMAPK1MAPTTP53POLB | |
| SCHEMBL23440286 | 0.77 | TSHR (1.00) | TSHRMAPK1EDNRBEDNRAMAPT | |
| SCHEMBL6150975 | 0.77 | EDNRA (1.00) | EDNRBEDNRA | |
| SCHEMBL1027519 | 0.76 | TSHR (0.83) | TSHRMAPK1MAPTPPIAALDH1A1 | |
| SCHEMBL6668835 | 0.75 | ALDH1A1 (0.49) | TSHRMAPK1MAPTPOLBPPIA | |
| SCHEMBL6667413 | 0.75 | TSHR (0.63) | TSHRMAPK1MAPTPPIAALDH1A1 | |
| SCHEMBL6664916 | 0.73 | ALDH1A1 (0.47) | TSHRMAPK1MAPTPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004021997-A2 | INHIBITORS OF FUNGAL INVASION | MICROBIA, INC. (US) | 2004-03-18 | — | — | WO | disclosed |