Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 17/20 | 0.64 |
| ▸ | FNTB | P49356 | 17/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6671324 | 0.78 | FNTA (1.00) | FNTAFNTB | |
| SCHEMBL24723386 | 0.78 | PKM (0.59) | FNTAFNTBMEN1KMT2ANPSR1 | |
| SCHEMBL1853982 | 0.76 | GAA (0.61) | FNTAFNTBMEN1KMT2ANPSR1 | |
| SCHEMBL6669170 | 0.76 | FNTA (0.92) | FNTAFNTB | |
| SCHEMBL25172584 | 0.75 | GAA (0.52) | FNTAFNTBMEN1KMT2ANPSR1 | |
| SCHEMBL6667023 | 0.75 | FNTA (1.00) | FNTAFNTB | |
| SCHEMBL24723809 | 0.74 | CDK4 (0.77) | FNTAFNTBMEN1KMT2ANPSR1 | |
| SCHEMBL18229448 | 0.74 | MEN1 (0.85) | FNTAFNTBMEN1KMT2A | |
| SCHEMBL30777136 | 0.74 | MEN1 (0.85) | FNTAFNTBMEN1KMT2A | |
| SCHEMBL6670532 | 0.73 | FNTA (1.00) | FNTAFNTBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1324985-A4 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2004-10-06 | — | — | EP | disclosed |
| EP-1324985-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 2003-07-09 | — | — | EP | disclosed |
| WO-2002028831-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2002-04-11 | — | — | WO | disclosed |