Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 2/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.73 |
| ▸ | MEN1 | O00255 | 3/20 | 0.73 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.68 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.62 |
| ▸ | FNTA | P49354 | 1/20 | 0.62 |
| ▸ | FNTB | P49356 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | TACR1 | P25103 | 1/20 | 0.60 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 2/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.57 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.57 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.57 |
| ▸ | MAOA | P21397 | 2/20 | 0.57 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.57 |
| ▸ | HTR1B | P28222 | 2/20 | 0.57 |
| ▸ | HTR2A | P28223 | 2/20 | 0.57 |
| ▸ | HTR2C | P28335 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25169836 | 0.88 | CDK4 (0.61) | CDK4KMT2AMEN1NPSR1ALDH1A1 | |
| SCHEMBL25491890 | 0.87 | HRH3 (0.60) | CDK4KMT2AMEN1NPSR1KDM4E | |
| SCHEMBL18229448 | 0.86 | MEN1 (0.85) | CDK4KMT2AMEN1SLC6A2FNTA | |
| SCHEMBL30777136 | 0.86 | MEN1 (0.85) | CDK4KMT2AMEN1SLC6A2FNTA | |
| SCHEMBL25491596 | 0.84 | NPSR1 (0.65) | CDK4KMT2AMEN1NPSR1SLC6A2 | |
| SCHEMBL24723324 | 0.83 | KDM4E (0.65) | CDK4KMT2AMEN1HTR1AHTR1B | |
| SCHEMBL8489403 | 0.83 | CDK4 (0.65) | CDK4KMT2AMEN1NPSR1SLC6A2 | |
| SCHEMBL1852400 | 0.83 | PKM (0.64) | CDK4KMT2AMEN1NPSR1SLC6A2 | |
| SCHEMBL29992703 | 0.83 | PKM (0.64) | CDK4KMT2AMEN1NPSR1SLC6A2 | |
| SCHEMBL1854926 | 0.82 | NPSR1 (0.62) | CDK4KMT2AMEN1NPSR1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260138947-A1 | BENZYLTRYPTAMINE COMPOUNDS | REUNION NEUROSCIENCE INC (US) | 2026-05-21 | — | — | US | disclosed |
| US-20260042735-A1 | BENZYLTRYPTAMINE COMPOUNDS | REUNION NEUROSCIENCE INC (US) | 2026-02-12 | — | — | US | disclosed |
| US-20240400510-A1 | NOVEL BENZYLTRYPTAMINE COMPOUNDS | REUNION NEUROSCIENCE INC (US) | 2024-12-05 | — | — | US | disclosed |
| EP-4423061-A1 | NOVEL BENZYLTRYPTAMINE COMPOUNDS | Reunion Neuroscience, Inc. (US) | 2024-09-04 | — | — | EP | disclosed |
| US-20240254081-A1 | CATALYTIC TRYPTAMINE PROCESSES AND PRECURSORS | KARE CHEMICAL TECHNOLOGIES INC. (CA) | 2024-08-01 | — | — | US | disclosed |
| CN-118382614-A | Novel benzyl tryptamine compounds | 瑞安神经科学公司 | 2024-07-23 | — | — | CN | disclosed |
| EP-4334285-A1 | CATALYTIC TRYPTAMINE PROCESSES AND PRECURSORS | Kare Chemical Technologies Inc. (CA) | 2024-03-13 | — | — | EP | disclosed |
| CN-117597329-A | Method for the catalytic synthesis of tryptamine and precursors thereof | 凯尔化学科技公司 | 2024-02-23 | — | — | CN | disclosed |
| US-20230144974-A1 | BENZYLTRYPTAMINE COMPOUNDS | REUNION NEUROSCIENCE INC. | 2023-05-11 | — | — | US | disclosed |
| US-20230144974-A1 | BENZYLTRYPTAMINE COMPOUNDS | REUNION NEUROSCIENCE INC. | 2023-05-11 | — | — | US | disclosed |
| US-20230144974-A1 | BENZYLTRYPTAMINE COMPOUNDS | REUNION NEUROSCIENCE INC. | 2023-05-11 | — | — | US | disclosed |
| WO-2023070228-A1 | NOVEL BENZYLTRYPTAMINE COMPOUNDS | REUNION NEUROSCIENCE CANADA INC. (CA) | 2023-05-04 | — | — | WO | disclosed |
| WO-2023070228-A1 | NOVEL BENZYLTRYPTAMINE COMPOUNDS | REUNION NEUROSCIENCE CANADA INC. (CA) | 2023-05-04 | — | — | WO | disclosed |
| WO-2022232931-A1 | CATALYTIC TRYPTAMINE PROCESSES AND PRECURSORS | KARE CHEMICAL TECHNOLOGIES INC. (CA) | 2022-11-10 | — | — | WO | disclosed |
| WO-2022232931-A1 | CATALYTIC TRYPTAMINE PROCESSES AND PRECURSORS | KARE CHEMICAL TECHNOLOGIES INC. (CA) | 2022-11-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240400510-A1 | NOVEL BENZYLTRYPTAMINE COMPOUNDS | HTR2C, HTR2A, HTR3B | CDK4 3790/4885KMT2A 1611/4885MEN1 1581/4885 |
| US-20240254081-A1 | CATALYTIC TRYPTAMINE PROCESSES AND PRECURSORS | HNMT, TPSB2, TPSG1 | CDK4 4041/4885KMT2A 390/4885MEN1 379/4885 |
| US-20260042735-A1 | BENZYLTRYPTAMINE COMPOUNDS | HTR2C, HTR2A, HTR6 | CDK4 3967/4885KMT2A 1101/4885MEN1 2882/4885 |
| US-20230144974-A1 | BENZYLTRYPTAMINE COMPOUNDS | HTR2C, HTR2A, HTR3B | CDK4 3723/4885KMT2A 1625/4885MEN1 1121/4885 |
| US-20260138947-A1 | BENZYLTRYPTAMINE COMPOUNDS | HTR2C, CNR2, HTR3B | CDK4 4144/4885KMT2A 1340/4885MEN1 2816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.