Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1919502 | 0.84 | TDP1 (0.50) | ALDH1A1HPGDCYP3A4HTTLMNA | |
| SCHEMBL5144939 | 0.82 | HTT (0.51) | ALDH1A1MAPK1HPGDCYP3A4HTT | |
| SCHEMBL17877001 | 0.82 | CA1 (0.43) | ALDH1A1HPGDLMNAKDM4EHSD17B10 | |
| SCHEMBL10746826 | 0.81 | ALDH1A1 (0.41) | ALDH1A1MAPK1HPGDCYP3A4HTT | |
| SCHEMBL17041239 | 0.81 | ALDH1A1 (0.41) | ALDH1A1MAPK1HPGDCYP3A4HTT | |
| SCHEMBL9720594 | 0.79 | L3MBTL1 (0.50) | ALDH1A1MAPK1HTTLMNAMAPT | |
| SCHEMBL12556197 | 0.78 | MAPT (0.49) | ALDH1A1MAPK1HPGDCYP3A4HTT | |
| SCHEMBL18739643 | 0.78 | HSD17B10 (0.55) | ALDH1A1MAPK1HPGDLMNAKDM4E | |
| SCHEMBL18073572 | 0.77 | KDM4E (0.41) | ALDH1A1MAPK1HPGDCYP3A4HTT | |
| SCHEMBL3768405 | 0.77 | TDP1 (0.47) | ALDH1A1MAPK1HTTLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160096795-A1 | COMPOUNDS AND METHODS FOR PREPARATION OF DIARYLPROPANES | UNIGEN INC (US) | 2016-04-07 | — | — | US | disclosed |
| US-9045405-B2 | Compounds and methods for preparation of diarylpropanes | UNIGEN, INC. (US) | 2015-06-02 | — | — | US | disclosed |
| US-20140235899-A1 | COMPOUNDS AND METHODS FOR PREPARATION OF DIARYLPROPANES | UNIGEN, INC. (US) | 2014-08-21 | — | — | US | disclosed |
| US-8586799-B2 | Compounds and methods for preparation of diarylpropanes | UNIGEN, INC. (US) | 2013-11-19 | — | — | US | disclosed |
| US-20120245393-A1 | COMPOUNDS AND METHODS FOR PREPARATION OF DIARYLPROPANES | UNIGEN, INC. (US) | 2012-09-27 | — | — | US | disclosed |
| EP-1133467-B1 | ION CHANNEL MODULATING AGENTS | NEUROSEARCH AS (DK) | 2004-09-15 | — | — | EP | disclosed |
| US-6458846-B1 | FOR USE IN THERAPY OF ASTHMA, CYSTIC FIBROSIS, CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND RHINORRHEA, CONVULSIONS, VASCULAR SPASMS, CORONARY ARTERY SPASMS, RENAL DISORDERS, POLYCYSTIC KIDNEY DISEASE, BLADDER SPASMS, ETC. | NEUROSEARCH A/S (DK) | 2002-10-01 | — | — | US | disclosed |
| US-20020058700-A1 | Ion channel modulating agents | NEUROSEARCH A/S (DK) | 2002-05-16 | — | — | US | disclosed |
| EP-1133467-A1 | ION CHANNEL MODULATING AGENTS | NEUROSEARCH A/S (DK) | 2001-09-19 | — | — | EP | disclosed |
| WO-2000034228-A1 | ION CHANNEL MODULATING AGENTS | NEUROSEARCH A/S (DK) | 2000-06-15 | — | — | WO | disclosed |
| US-5403823-A | Fragrant musk-like aroma | UNION CAMP CORPORATION (US) | 1995-04-04 | — | — | US | disclosed |
| WO-1995000113-A1 | NOVEL FORMATE ESTER INDANE COMPOUNDS | UNION CAMP CORPORATION (US) | 1995-01-05 | — | — | WO | disclosed |
| US-5292720-A | Formate ester indane compounds | UNION CAMP CORPORATION (US) | 1994-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160096795-A1 | COMPOUNDS AND METHODS FOR PREPARATION OF DIARYLPROPANES | DDT, QDPR, NPY1R | ALDH1A1 2064/4885MAPK1 4107/4885HPGD 692/4885 |
| US-20120245393-A1 | COMPOUNDS AND METHODS FOR PREPARATION OF DIARYLPROPANES | DDT, QDPR, NPY1R | ALDH1A1 2064/4885MAPK1 4107/4885HPGD 692/4885 |
| US-20140235899-A1 | COMPOUNDS AND METHODS FOR PREPARATION OF DIARYLPROPANES | DDT, QDPR, NPY1R | ALDH1A1 2064/4885MAPK1 4107/4885HPGD 692/4885 |
| US-20020058700-A1 | Ion channel modulating agents | KCNN4, KCNN1, KCNJ2 | ALDH1A1 3163/4885MAPK1 762/4885HPGD 678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.