Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | PPIA | P62937 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | GFER | P55789 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23440286 | 0.81 | TSHR (1.00) | TSHRMAPK1ALDH1A1MAPTADRA1A | |
| SCHEMBL6667895 | 0.80 | MAPK1 (0.64) | TSHRMAPK1ALDH1A1MAPTPOLB | |
| SCHEMBL6669175 | 0.79 | TSHR (0.63) | TSHRMAPK1ALDH1A1MAPTPOLB | |
| SCHEMBL6667413 | 0.79 | TSHR (0.63) | TSHRMAPK1ALDH1A1MAPTADRA1A | |
| SCHEMBL6685181 | 0.79 | TSHR (0.70) | TSHRMAPK1ALDH1A1MAPTPOLB | |
| SCHEMBL12879697 | 0.78 | ALDH1A1 (0.77) | TSHRMAPK1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL1027519 | 0.78 | TSHR (0.83) | TSHRMAPK1ALDH1A1MAPTADRA1A | |
| SCHEMBL6672003 | 0.78 | POLB (0.63) | TSHRMAPK1ALDH1A1MAPTPOLB | |
| SCHEMBL6665288 | 0.78 | TSHR (0.77) | TSHRMAPK1ALDH1A1MAPTADRA1A | |
| SCHEMBL6669545 | 0.78 | TSHR (0.68) | TSHRMAPK1ALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004021997-A2 | INHIBITORS OF FUNGAL INVASION | MICROBIA, INC. (US) | 2004-03-18 | — | — | WO | disclosed |