Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6666893 | 0.79 | NPC1 (0.74) | POLBTSHRMAPK1KMT2AMAPT | |
| SCHEMBL6680802 | 0.78 | MAPT (0.60) | POLBTSHRMAPK1KMT2AMAPT | |
| SCHEMBL6667922 | 0.78 | TSHR (0.68) | POLBL3MBTL1TSHRMAPK1KMT2A | |
| SCHEMBL6666219 | 0.78 | MAPT (0.60) | POLBTSHRMAPK1KMT2AMAPT | |
| SCHEMBL6685106 | 0.76 | TSHR (0.73) | TSHRMAPK1KMT2AMAPTALDH1A1 | |
| SCHEMBL6670051 | 0.75 | KMT2A (0.59) | POLBTSHRMAPK1KMT2AMAPT | |
| SCHEMBL6669899 | 0.75 | MAPT (0.56) | POLBTSHRMAPK1KMT2AMAPT | |
| SCHEMBL15831621 | 0.75 | ALDH1A1 (0.62) | POLBTSHRMAPK1KMT2AMAPT | |
| SCHEMBL6668899 | 0.74 | HTT (0.60) | POLBTSHRMAPK1KMT2AMAPT | |
| SCHEMBL6680042 | 0.74 | MAPT (0.55) | POLBTSHRMAPK1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004021997-A2 | INHIBITORS OF FUNGAL INVASION | MICROBIA, INC. (US) | 2004-03-18 | — | — | WO | disclosed |