Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9228424 | 0.89 | ESR1 (0.36) | ESR1ESR2FAAHCA1CA2 | |
| SCHEMBL842106 | 0.85 | ESR1 (0.36) | ESR1ESR2FAAHCA1CA2 | |
| SCHEMBL6672072 | 0.83 | L3MBTL1 (0.50) | ESR1ESR2TSHRMAPK1ATM | |
| SCHEMBL927436 | 0.76 | IDO1 (0.33) | ESR1ESR2FAAHCA1CA2 | |
| SCHEMBL11837305 | 0.76 | ESR1 (0.37) | ESR1ESR2FAAHCA1CA2 | |
| SCHEMBL27866288 | 0.76 | TSHR (0.32) | ESR1ESR2TSHRMAPK1ATM | |
| SCHEMBL927504 | 0.76 | TSHR (0.32) | ESR1ESR2TSHRMAPK1ATM | |
| SCHEMBL51783 | 0.75 | IDO1 (0.52) | FAAHCA1CA2TSHRMAPK1 | |
| SCHEMBL1579690 | 0.75 | — | — | |
| SCHEMBL11839524 | 0.73 | ESR1 (0.38) | ESR1ESR2FAAHCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0969007-B1 | Method of making an aromatic chlorosilane compound by a hydrosilation reaction | DOW CORNING ASIA LTD (JP) | 2004-09-22 | — | — | EP | disclosed |
| US-6054602-A | Method of making an aromatic chlorosilane compound by a hydrosilation reaction | DOW CORNING ASIA, LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| EP-0969007-A2 | Method of making an aromatic chlorosilane compound by a hydrosilation reaction | Dow Corning Asia, Ltd. (JP) | 2000-01-05 | — | — | EP | disclosed |