Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLA1 | P09884 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7845993 | 0.83 | KCNH2 (0.43) | KDM4EALDH1A1HPGDMAPTPOLB | |
| SCHEMBL6667414 | 0.83 | ALDH1A1 (0.44) | KDM4EALDH1A1HPGDMAPTPOLB | |
| SCHEMBL6701500 | 0.83 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDMAPTPOLB | |
| SCHEMBL6673054 | 0.83 | ALDH1A1 (0.56) | KDM4EALDH1A1HPGDMAPTPOLB | |
| SCHEMBL7843014 | 0.81 | ALDH1A1 (0.43) | KDM4EALDH1A1HPGDMAPTPOLB | |
| SCHEMBL6670167 | 0.79 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDMAPTPOLB | |
| SCHEMBL7848232 | 0.79 | KCNH2 (0.46) | KDM4EALDH1A1HPGDMAPTPOLB | |
| SCHEMBL7848276 | 0.78 | KDM4E (0.46) | KDM4EALDH1A1HPGDMAPTPOLB | |
| SCHEMBL6205197 | 0.78 | POLB (0.61) | KDM4EALDH1A1HPGDMAPTPOLB | |
| SCHEMBL6667855 | 0.78 | KMT2A (0.47) | KDM4EALDH1A1HPGDMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004019932-A1 | METHOD OF PREVENTING OR TREATING ATHEROSCLEROSIS OR RESTENOSIS | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-11 | — | — | WO | claimed |
| WO-2004019932-A1 | METHOD OF PREVENTING OR TREATING ATHEROSCLEROSIS OR RESTENOSIS | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-11 | — | — | WO | disclosed |