Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLA1 | P09884 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6670167 | 0.94 | ALDH1A1 (0.49) | KCNH2KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL7848276 | 0.93 | KDM4E (0.46) | KCNH2KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL7834741 | 0.91 | KDM4E (0.45) | KCNH2KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL7845993 | 0.89 | KCNH2 (0.43) | KCNH2KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL6701500 | 0.83 | ALDH1A1 (0.46) | KCNH2KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL6673054 | 0.81 | ALDH1A1 (0.56) | KCNH2KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL7841393 | 0.81 | NHERF1 (0.42) | KDM4EMAPTPOLBHSD17B10 | |
| SCHEMBL7843014 | 0.81 | ALDH1A1 (0.43) | KCNH2KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL6667865 | 0.80 | KMT2A (0.48) | KCNH2KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL6667855 | 0.79 | KMT2A (0.47) | KCNH2KDM4EALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140850-A1 | QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000040561-A1 | QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-13 | — | — | WO | disclosed |