Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.50 |
| ▸ | POLA1 | P09884 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6205197 | 0.86 | POLB (0.61) | ALDH1A1KDM4EHPGDMAPTSMN1; SMN2 | |
| SCHEMBL6668160 | 0.84 | KMT2A (0.49) | ALDH1A1KDM4EHPGDMAPTKMT2A | |
| SCHEMBL6204455 | 0.83 | POLB (0.53) | ALDH1A1KDM4EHPGDMAPTSMN1; SMN2 | |
| SCHEMBL6667777 | 0.83 | RAB9A (0.55) | KDM4EMAPTKMT2AGAAKCNH2 | |
| SCHEMBL6668355 | 0.83 | KDM4E (0.44) | ALDH1A1KDM4EHPGDMAPTKMT2A | |
| SCHEMBL6667855 | 0.82 | KMT2A (0.47) | ALDH1A1KDM4EHPGDMAPTKMT2A | |
| SCHEMBL6667927 | 0.82 | KMT2A (0.50) | ALDH1A1KDM4EHPGDMAPTKMT2A | |
| SCHEMBL6670167 | 0.81 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDMAPTKMT2A | |
| SCHEMBL7848232 | 0.81 | KCNH2 (0.46) | ALDH1A1KDM4EHPGDMAPTKMT2A | |
| SCHEMBL6667865 | 0.81 | KMT2A (0.48) | ALDH1A1KDM4EHPGDMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004019932-A1 | METHOD OF PREVENTING OR TREATING ATHEROSCLEROSIS OR RESTENOSIS | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-11 | — | — | WO | claimed |