SCHEMBL6668549

SCHEMBL6668549

OB(O)Oc1ccc2c(c1)CN(C(c1ccccc1)(c1ccccc1)c1ccccc1)C2

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DRD1 P21728 1/20 0.31
DRD5 P21918 1/20 0.31
OPRM1 P35372 1/20 0.31
OPRD1 P41143 1/20 0.31
HDAC8 Q9BY41 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3885146 0.81 CCR6 (0.40)
SCHEMBL6672259 0.80 KCNH2 (0.30)
SCHEMBL6670190 0.79 DYRK1A (0.34) DRD1
SCHEMBL383295 0.75 HSD17B3 (0.40)
SCHEMBL6669355 0.74 SLC6A4 (0.38) DRD1DRD5
SCHEMBL564940 0.72 DPP7 (0.34)
SCHEMBL10269553 0.72 ALDH1A1 (0.33)
SCHEMBL16249200 0.69 KMT2A (0.45) DRD1DRD5
SCHEMBL13028023 0.66 KCNH2 (0.43) DRD1DRD5
SCHEMBL2141558 0.66 MAPT (0.49)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1227096-B1 4-OXOQUINOLIZINE ANTIMICROBIALS HAVING 2-PYRIDONE SKELETONS AS THE PARTIAL STRUCTURE SATO PHARMA (JP) 2004-09-22 EP disclosed
US-6525066-B2 Bactericides; side effect reduction SATO PHARMACEUTICAL CO., LTD. (JP) 2003-02-25 US disclosed
US-20020173517-A1 4-Oxoquinolizine antimicrobial having 2-pyridone skeleton as partial structure SATO PHARMACEUTICAL CO., LTD. (JP) 2002-11-21 US disclosed
EP-1227096-A1 4-OXOQUINOLIZINE ANTIMICROBIALS HAVING 2-PYRIDONE SKELETONS AS THE PARTIAL STRUCTURE Sato Pharmaceutical Co. Ltd. (JP) 2002-07-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020173517-A1 4-Oxoquinolizine antimicrobial having 2-pyridone skeleton as partial structure IL4I1, TLR5, IFNG DRD1 285/4885DRD5 218/4885OPRM1 548/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.