SCHEMBL6668560

SCHEMBL6668560

CC1(C)COCC(=O)OC1

nearest known ligand 0.34

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GABRP O00591 1/20 0.34
GABRD O14764 1/20 0.34
GABRA1 P14867 1/20 0.34
GABRB1 P18505 1/20 0.34
GABRG2 P18507 1/20 0.34
GABRB3 P28472 1/20 0.34
GABRA5 P31644 1/20 0.34
GABRA3 P34903 1/20 0.34
GABRA2 P47869 1/20 0.34
GABRB2 P47870 1/20 0.34
GABRA4 P48169 1/20 0.34
GABRE P78334 1/20 0.34
GABRA6 Q16445 1/20 0.34
GABRG1 Q8N1C3 1/20 0.34
GABRG3 Q99928 1/20 0.34
GABRQ Q9UN88 1/20 0.34
LMNA P02545 1/20 0.30
CYP2C9 P11712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6672722 1.00 GABRP (0.34) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL11443083 0.77 GABRP (0.38) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL7113337 0.77 LMNA (0.45) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL360166 0.73 CA1 (0.50) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL45972 0.72
SCHEMBL9265626 0.71 CA1 (0.48) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL11536217 0.71 CA1 (0.48) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL1013574 0.71
SCHEMBL17603299 0.71 TP53 (0.32) GABRPGABRDGABRA1GABRB1GABRG2
Ethylene SCHEMBL29492957 0.70 CA1 (0.46) GABRPGABRDGABRA1GABRB1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1074270-B1 Surgical multifilament construction ETHICON INC (US) 2003-09-17 EP claimed
EP-1074270-A1 Surgical multifilament construction ETHICON, INC. (US) 2001-02-07 EP claimed
US-6183499-B1 Surgical filament construction ETHICON, INC. 2001-02-06 US claimed
US-5844067-A Process for producing absorbable segmented copolymers with a substantially uniform sequence distribution ETHICON, INC. 1998-12-01 US claimed
EP-0802211-A2 A proecess for producing bioabsorbable segmented copolymers with a substantiallyuniform sequence distribution ETHICON, INC. (US) 1997-10-22 EP claimed
CN-112261957-A Biocompatible, heat and gamma radiation stable medical device lubricants and corrosion inhibitors 德普伊新特斯产品公司 2021-01-22 CN disclosed
EP-0795573-B1 Absorbable copolymers and blends of 6,6-dialkyl-1,4-dioxepan-2-one and its cyclic dimer ETHICON INC (US) 2004-09-29 EP disclosed
EP-1074270-B1 Surgical multifilament construction ETHICON INC (US) 2003-09-17 EP disclosed
EP-0830866-B1 Process for manufacturing sutures from copolymers of glycolide and epsilon-caprolactone ETHICON INC (US) 2002-12-11 EP disclosed
EP-1074270-A1 Surgical multifilament construction ETHICON, INC. (US) 2001-02-07 EP disclosed
US-6183499-B1 Surgical filament construction ETHICON, INC. 2001-02-06 US disclosed
US-5844067-A Process for producing absorbable segmented copolymers with a substantially uniform sequence distribution ETHICON, INC. 1998-12-01 US disclosed
EP-0830866-A2 Process for manufacturing sutures from copolymers of glycolide and epsilon-caprolactone ETHICON, INC. (US) 1998-03-25 EP disclosed
US-5718716-A TENSILE STRENGTH, LOW MODULUS ETHICON, INC. (US) 1998-02-17 US disclosed
US-5703200-A Absorbable copolymers and blends of 6,6-dialkyl-1,4-dioxepan-2-one and its cyclic dimer ETHICON, INC. (US) 1997-12-30 US disclosed
EP-0802211-A2 A proecess for producing bioabsorbable segmented copolymers with a substantiallyuniform sequence distribution ETHICON, INC. (US) 1997-10-22 EP disclosed
EP-0795573-A2 Absorbable copolymers and blends of 6,6-dialkyl-1,4-dioxepan-2-one and its cyclic dimer ETHICON, INC. (US) 1997-09-17 EP disclosed