SCHEMBL45972

SCHEMBL45972

CC1(C)COC(=O)C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7113337 0.78 LMNA (0.45)
SCHEMBL11443083 0.78 GABRP (0.38)
SCHEMBL439908 0.76 GABRP (0.45)
SCHEMBL20079555 0.74
SCHEMBL360166 0.74 CA1 (0.50)
SCHEMBL438928 0.74
SCHEMBL758910 0.74
SCHEMBL6555571 0.74
SCHEMBL9265626 0.72 CA1 (0.48)
SCHEMBL11536217 0.72 CA1 (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 301 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113862768-A Pore-forming method for titanium alloy surface, titanium alloy-plastic complex and preparation method 深圳市鑫鸿达清洗技术有限公司 2021-12-31 CN claimed
WO-2006052985-A1 LACTONES AS NEW OXYGENATE FUEL ADDITIVES, FUELS BASED THEREON AND METHODS FOR USING SAME THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2006-05-18 WO claimed
US-5319102-A Pre-and postemergence UNIROYAL CHEMICAL COMPANY, INC. (US) 1994-06-07 US claimed
EP-0004493-B1 ETHERS WHOSE ORGANIC MOIETIES HAVE ASYMMETRIC ATOMS, METHODS FOR THEIR PREPARATION AND THEIR USE FOR THE RESOLUTION OF ALCOHOLS, PHENOLS OR CERTAIN COMPOUNDS WITH A LACTONE STRUCTURE ROUSSEL-UCLAF (FR) 1981-05-06 EP claimed
EP-0004493-A1 Ethers whose organic moieties have asymmetric atoms, methods for their preparation and their use for the resolution of alcohols, phenols or certain compounds with a lactone structure ROUSSEL-UCLAF (FR) 1979-10-03 EP claimed
JP-55129277-A None JP disclosed
CN-112142694-B Polysubstituted tetrahydrofuran and tetrahydropyran diene compound and preparation method thereof 中国科学院成都有机化学有限公司 2025-06-10 CN disclosed
US-20250034120-A1 PYRIDAZINONES AS PARP7 INHIBITORS RIBON THERAPEUTICS, INC. 2025-01-30 US disclosed
CN-118562626-A Trichoderma citrinoviride strain capable of producing various furanones and screening culture method and application thereof 江苏今世缘酒业股份有限公司 2024-08-30 CN disclosed
CN-115160352-B Double-function catalyst derived from hydrogenated cinchona alkaloid and preparation and application thereof 万华化学集团股份有限公司 2023-12-19 CN disclosed
EP-4234551-A2 PYRIDAZINONES AS PARP7 INHIBITORS Ribon Therapeutics Inc. (US) 2023-08-30 EP disclosed
US-20230192664-A1 PYRIDAZINONES AS PARP7 INHIBITORS ANKURA TRUST COMPANY, LLC, AS COLLATERAL TRUSTEE 2023-06-22 US disclosed
EP-0155002-B1 HYDROFORMYLATION OF 3-METHYL-3-BUTEN-1-OL AND USE OF SUCH HYDROFORMYLATION PRODUCTS KURARAY CO., LTD. (JP) 1989-09-13 EP disclosed
US-4861922-A Hydroformylation of 3-methyl-3-buten-1-ol and analogs thereof and use of such hydroformylation products KURARAY COMPANY, LTD. (JP) 1989-08-29 US disclosed
US-4663468-A RHODIUM CATALYST, COPPER AND ZINC OR CHROMIUM OXIDES CATALYST KURARAY COMPANY, LTD. (JP) 1987-05-05 US disclosed
US-4596879-A Process for producing intermediate furanones from diol derivative and thionyl chloride HOFFMANN-LA ROCHE INC. (US) 1986-06-24 US disclosed
EP-0172371-A1 Process for the preparation of dehydroxypantolactone F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1986-02-26 EP disclosed
EP-0004493-B1 ETHERS WHOSE ORGANIC MOIETIES HAVE ASYMMETRIC ATOMS, METHODS FOR THEIR PREPARATION AND THEIR USE FOR THE RESOLUTION OF ALCOHOLS, PHENOLS OR CERTAIN COMPOUNDS WITH A LACTONE STRUCTURE ROUSSEL-UCLAF (FR) 1981-05-06 EP disclosed
JP-S55129277-A PREPARATION OF R-( )-PANTOLACTONE FUJI YAKUHIN KOGYO KK 1980-10-06 JP disclosed
EP-0004493-A1 Ethers whose organic moieties have asymmetric atoms, methods for their preparation and their use for the resolution of alcohols, phenols or certain compounds with a lactone structure ROUSSEL-UCLAF (FR) 1979-10-03 EP disclosed