Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 6/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 4/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | PYGL | P06737 | 1/20 | 0.31 |
| ▸ | PYGM | P11217 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3655671 | 0.83 | LOXL2 (0.40) | NR3C1PGRNR3C2 | |
| SCHEMBL5801773 | 0.80 | NR3C1 (0.37) | NR3C1PGRNR3C2CYP3A4 | |
| SCHEMBL3707342 | 0.80 | NR3C1 (0.45) | NR3C1PGRNR3C2CYP3A4 | |
| SCHEMBL3714468 | 0.77 | NR3C1 (0.50) | NR3C1PGRNR3C2CYP3A4 | |
| SCHEMBL6668591 | 0.77 | NR3C1 (0.57) | NR3C1ARHRH4PGRNR3C2 | |
| SCHEMBL4044986 | 0.76 | NR3C1 (0.45) | NR3C1PGRNR3C2CYP3A4 | |
| SCHEMBL4223561 | 0.75 | NR3C1 (0.35) | NR3C1PGRNR3C2CYP3A4 | |
| SCHEMBL3709591 | 0.74 | NR3C1 (0.50) | NR3C1PGRNR3C2CYP3A4 | |
| SCHEMBL4037364 | 0.74 | NR3C1 (0.42) | NR3C1ARHRH4PGRNR3C2 | |
| SCHEMBL6669369 | 0.73 | NR3C1 (0.53) | NR3C1PGRNR3C2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490062-A1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2004-12-29 | — | — | EP | claimed |
| WO-2003082280-A1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2003-10-09 | — | — | WO | claimed |